“…Some studies completely denied this association, and the others explained it as based solely on the increase in the prevalence of both ELC and CAD with advancing age [8, 9, 10, 11]. Overfield and Call [15] reported that ELC developed with age in healthy adults, and the frequency of occurrence of different earlobe shapes differs by race. Most of the studies were based on clinical criteria for the diagnosis of CAD [8, 9, 10, 11, 12, 14]or were only based on known risk factors for the disease [1, 5, 16, 17, 18, 19, 20].…”