Early application of CVVH In the complex treatment of patients with early severe acute pancreatitis

High‐volume hemofiltration reduces short‐term mortality with no influence on the incidence of MODS, hospital stay, and hospitalization cost in patients with severe‐acute pancreatitis: A meta‐analysis

“…The results of each subgroup were as follows: the HVHF group: OR = 2.55, 95% CI [1.47‐4.44], P = .0009, I 2 = 0%; the non‐HVHF group: OR = 1.12, 95% CI [0.73‐1.73], P = .60, I 2 = 42%; prospective studies: OR = 2.26, 95% CI [1.48‐3.46], P = .002, I 2 = 0%; retrospective studies: OR = 1.12, 95% CI [0.69‐1.82], P = .64, I 2 = 63%. After excluding the study by Alekasandrova et al, 27 the OR, 95% CI, and P values remained unchanged and I 2 value was 40%. Then, as the study by Abe et al was excluded, there was no significant difference in the values of OR and 95% CI, but the I 2 value was 0%.…”

“…The short‐term mortality is also shown: OR = 1.76, 95% CI [1.20‐2.57], P = .004, I 2 = 63%. After excluding the study by Alekasandrova et al, 27 the OR, 95% CI, and P values remained unchanged and the I 2 value was 20%. The long‐term mortality is as follows: OR = 1.99, 95% CI [0.70‐5.76], P = .20, I 2 = 0%.…”

“…After excluding the study by Alekasandrova et al,27 the OR, 95% CI, and P values remained unchanged and I 2 value was 40%. Then, as the study by Abe et al was excluded, there was no significant difference in the values of OR and 95% CI, but the I…”

“…A total of 204 studies were identified using the searching strategies. Among them, 185 studies were excluded (Figure 1), leaving 11 prospective studies 4,12‐21 and 6 retrospective studies 22‐27 for analysis. Studies by Wang et al and Alekasandrova et al 19,27 had two subgroups, which could be considered as two independent studies.…”

“…Among them, 185 studies were excluded (Figure 1), leaving 11 prospective studies 4,12-21 and 6 retrospective studies [22][23][24][25][26][27] for analysis. Studies by Wang et al and Alekasandrova et al 19,27 had two subgroups, which could be considered as two independent studies. Therefore, a total of 19 studies were analyzed.…”