Early Cancer Diagnosis by Image Processing Sensors Measuring the Conductive or Radiative Heat

Gavriloaia, Gheorghe; Ghemigian, A. M.; Hurduc, Anca

doi:10.1007/978-3-540-92841-6_105

Cited by 4 publications

(5 citation statements)

References 8 publications

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“…Research investigating the feasibility of thermography for the complementary diagnosis of thyroid cancer is still recent. In addition, some studies that have indicated an increase in temperature in diverse types of thyroid tumors have been identified [ 17 – 19 ]. When compared with conventional exams, such as ultrasonography, FNA and Doppler, the thermographic exam appears to be effective, with 100% sensitivity, surpassing the Doppler exam in the selection of thyroid nodules [ 18 ].…”

Section: Introductionmentioning

confidence: 99%

“…When compared with conventional exams, such as ultrasonography, FNA and Doppler, the thermographic exam appears to be effective, with 100% sensitivity, surpassing the Doppler exam in the selection of thyroid nodules [ 18 ]. A more complex study with image processing conveyed a good percentage of accuracy for cancer diagnosis, calculated at around 78% to 89% [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

“…The studies conducted have found good results in pointing out thermal changes in the region with nodules when compared to healthy tissue [ 18 , 19 ]. However, the thermal difference between malignant and benign nodules and whether it is possible to differentiate the two types of nodules still represent a gap in the literature.…”

Section: Introductionmentioning

confidence: 99%

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Thermography as an aid for the complementary diagnosis of nodules in the thyroid gland

et al. 2022

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Background Considering the estimate that thyroid cancer will become the fourth most prevalent type of tumor, improving its diagnosis is a necessity. The gold standard for evaluating thyroid nodules is ultrasound followed by biopsy. These tests, however, have limitations, especially in nodules smaller than 0.5 cm. Dynamic infrared thermography is an imaging method that does not require ionizing radiation or contrast injection. The aim of the study was to analyze the thermal behavior of thyroid nodules through infrared thermography using the cold stress protocol. Results The Wilcoxon test showed thermal differences between groups (control and healthy, p < 0.001). The difference in the thermal behavior of the nodular tissues was evidenced by the longitudinal analysis. When comparing the nodules, it was possible to verify that the beginnings of tissue heating is significant (p = 0.001). In addition, the variability analysis showed a “well” effect, which occurred in period t-1 (pre-cooling time) to period t = 3 (time three minutes). Benign nodules had a variation ratio of 1.81 compared to malignant nodules. Conclusion Benign nodules present a different thermal behavior than malignant nodules, and both present different behavior than normal tissue. For the analysis of nodules, the protocol used with cold stress, dynamic thermography and the inclusion of time t-1 were essential for the differentiation of nodules in the thyroid gland. Therefore, we recommend the continuance of these parameters for future studies. Methods Thirty-three individuals with nodules in the thyroid region and nine healthy individuals participated in this descriptive exploratory study. In total, 42 nodules were evaluated, 11 malignant and 31 benign. The region of interest was exposed to cold stress for 30 s. First, the image was captured before the cold stress and subsequently, the images were assessed every 30 s, over a 10-min time period after cold stress. The perfusion and the thermal behavior of the tissues were evaluated by longitudinal analysis based on the number of pixels in each time period. The statistical tests of Wilcoxon, F-Snedecor and longitudinal models would assist in data analysis.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Thermography as an aid for the complementary diagnosis of nodules in the thyroid gland

et al. 2022

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“…The thermogram has a symmetrical pattern about the sagittal plane. In the case of soft tissue defects, spots with higher temperature appear in the thermal image, hence the symmetrical pattern vanishes …”

Section: Introductionmentioning

confidence: 99%

Analysis of thyroid thermographic images for detection of thyroid tumor: An experimental‐numerical study

Bahramian

Mojra

2019

Numer Methods Biomed Eng

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Thermography is a developing and noninvasive medical imaging technique that can be used for diagnosis of body disorders based on temperature deviation from normal body temperature. This research investigates the feasibility of thermography method in conjunction with artificial neural networks (ANNs) for detection of thyroid tumors. For this purpose, first, a 3-D model of the healthy human neck is constructed based on patient-specific computed tomography (CT) images. This model is used for analyzing bio-heat transfer in the human neck. The healthy thyroid gland is considered as a heat source

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“…Lawson and Chughtai (1963) established that the local difference in temperature over an embedded tumor was due to convection effects associated with increased blood perfusion and the increased metabolism around the tumor. Gavriloaia, Ghemigian, and Hurduc (2009) used a very sensitive sensor, composed by a video camera showing its spatial position and a special computer fusion program, which were used for early cancer diagnosis. By using high-resolution maps, the diagnosis for about 78.4% of patients with thyroid cancer, and more than 89.6% from patients with breast cancer, were correct.…”

Section: Introductionmentioning

confidence: 99%

Numerical two-dimensional thermal analysis of the human skin using the multigrid method

Ströher

Santiago

2019

Acta Sci. Technol.

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Heat can be used as an adjuvant treatment of many diseases and also as a powerful tool to help diagnose cancers, with the advantage to be a noninvasive exam. Some tumors may be best diagnosed by evaluating body temperature distribution, for instance, it is observed that local temperatures of the skin over a tumor are higher than the average skin temperature. Certainly, it is expected from medical diagnostics to be, early, fast and very precise. Especially if the health problem is a tumor, it is necessary to know the shape and the size of the cancer. Thermal images can provide further information about the tumor, generally, the thermal diagnostic is made comparing images of the region with a bioheat model. In this context, the present study shows interesting results about the multigrid method applied to solve the Pennes bioheat equation in two dimensions, using a non-stationary and steady state cases for the skin heath and with melanoma. The multigrid method presented itself as an extremely efficient and fast tool to solve the bioheat equation with refined grids that provide good spatial precision.

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Early Cancer Diagnosis by Image Processing Sensors Measuring the Conductive or Radiative Heat

Cited by 4 publications

References 8 publications

Thermography as an aid for the complementary diagnosis of nodules in the thyroid gland

Thermography as an aid for the complementary diagnosis of nodules in the thyroid gland

Analysis of thyroid thermographic images for detection of thyroid tumor: An experimental‐numerical study

Numerical two-dimensional thermal analysis of the human skin using the multigrid method

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