Early carotid endarterectomy in patients with a nondisabling ischemic stroke: Results of a retrospective analysis

Abstract

Our results suggest that selected patients with a minor stroke (mRS < or = 2 on admission) can safely undergo early CEA.

The Timing of Carotid Endarterectomy Post Stroke

“…The timing of surgery does not seem to influence the benefit of the CEA.'' Wolfle and coworkers [21] note similar results in a retrospective series of 66 patients who were neurologically stable and undergoing CEA for greater than 50% symptomatic stenosis after a mean interval of 10 days post stroke. They reported an operative mortality of 0% and (mostly) transient neurologic worsening in 5 (12.1%) patients, with resolution of symptoms within 4 days in 80%.…”

“…In their series of 66 patients undergoing CEA after stroke, Wolfle and coworkers [21] note, ''no correlation between timing of surgery or the presence of acute ipsilateral cranial CT defects with the occurrence of postoperative stroke.'' Similarly, in their study of 200 patients undergoing CEA within 6 months of a stroke, Paty and colleagues [13] note, ''no correlation between timing of surgery, extent of infarct on computed tomography/magnetic resonance imaging, and postoperative neurologic complications with the occurrence of postoperative stroke.''…”

American Society of Anesthesiology and Rankin as Predictive Parameters for the Outcome of Carotid Endarterectomy Within 28 Days After an Ischemic Stroke

“…[4][5][6] Because the study populations and the questions of interest were similar among the 3 trials, we performed a combined data analysis to achieve an adequate number of patients and increase the statistical power.…”

Urgent carotid endarterectomy to prevent recurrence and improve neurologic outcome in mild-to-moderate acute neurologic events

“…Nevertheless, recent studies have emphasized the safety of early CEA in patients with nondisabling stroke or acute neurologic events. [3][4][5][6][7] Moreover, previous reports on early CEA 8,9 have shown that expedited carotid revascularization can improve neurologic outcome, as evaluated by the National Institutes of Health Stroke Scale (NIHSS), probably recruiting brain areas that can be reperfused before cell death occurs. The aim of this prospective study was to evaluate the safety and benefit of urgent CEA in a consecutive series of patients presenting with carotid disease and a mild or moderate acute stable neurologic event.…”