Nearly 2,3 billion people suffer from carious lesions on permanent teeth, and approximately 530 million children suffer from carious lesions on deciduous teeth, even though dental caries is a preventable, reversible disease in its early stages. This study aimed to increase precision in early, reversible stage caries diagnosis, regardless of the examiners experience level. The main objectives were to test the intra- and inter-rater agreements of International Caries Assessment and Detection System (ICDAS) scores assigned during clinical examination and on 3D virtual models acquired using three types of intraoral scanners (Medit i500, Virtuo Vivo by Straumann, and Omnicam), their corresponding ICDAS scores based on clinical examinations, as well as their corresponding DIAGNOdent scores as they were recorded by examiners on three different levels of expertise (dental students, interns, and senior dentists). A total of 24 patients aged between 21 and 34 years, randomly selected from dental students and interns, underwent five examinations (three intraoral scannings, DIAGNOdent, and clinical examination), and the corresponding ICDAS scores and DIAGNOdent scores were recorded by a randomly selected rater out of the 31 available examiners. Inter-rater agreement and intra-rater agreement tests for ordinal data were chosen using Fleiss kappa coefficient. Cohen weighted kappa test was also used. Intra-rater and inter-rater agreement tests and inter-class correlations performed for all examination techniques showed statistically significant results (p<0.005). The highest positive interclass correlation was obtained for inter-rater agreement tests of 288 observations recorded by senior dentists (ICC=0.968). There were no statistically significant differences between the five types of examinations. To the authors knowledge, this is the first published study to test inter- and intra-rater agreement for ICDAS codes assigned by examining 3D virtual models. Using any of the three types of intraoral scanners tested in the study, real-time correlations and corrections, if necessary, of intraoral scanning data, clinical examination, and DIAGNOdent recording, are possible; thus, an accurate diagnosis can be achieved based on three different assessment methods for early stage caries.