Early childhood MRI findings in complex partial seizures and hippocampal sclerosis

Risse, J. H.; Menzel, Christian; Grünwald, Frank; Brechtelsbauer, Dierk; Ostertun, B.; Kuczaty, Stefan; Biersack, Hans‐Jürgen

doi:10.1002/(sici)1522-2586(199907)10:1<93::aid-jmri13>3.0.co;2-c

Cited by 3 publications

(1 citation statement)

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“…Cerebral hemiatrophy and tuberous sclerosis are easy to diagnose due to their characteristic appearances. Vascular malformations can be detected without any difficulty on MRI; however, developmental venous anomalies and the other occult vascular malformations can be easily missed [4,6,14,15,16,17,18,19]. Epileptogenic foci associated with medically intractable epilepsy syndromes can be assessed on MRI with high detection rates.…”

Section: Discussionmentioning

confidence: 99%

MR imaging in epilepsy that is refractory to medical therapy

et al. 2002

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The aim of this study was the assessment of detection rate on MRI and description of MRI findings in patients with medically intractable epilepsy. Seventy-three patients with medically intractable epilepsy between the ages of 0 and 68 years old were evaluated by MRI, on three planes with spin-echo T1, fast spin-echo T2, and fluid-attenuated inversion recovery sequences, and, if necessary, with contrast-enhanced SE T1 sequences. Cerebral infarct regions with atrophy and gliosis in 8 patients, cerebral tumors in 5 patients, hippocampal sclerosis in 16 patients, radial microbrain in 1 patient, cortical dysplasia in 3 patients, pachygyria in 2 patients, subcortical heterotopia in 2 patients, schizencephaly in 3 patients, cerebral hemiatrophy in 2 patients, tuberous sclerosis in 1 patient, herpes encephalitis in 2 patients, Rasmussen's encephalitis in 1 patient, vascular malformations in 5 patients, and no abnormality in 22 patients were detected. Magnetic resonance imaging has a high success rate in detecting structural brain abnormalities, of both temporal and extratemporal locations, associated with medically intractable epilepsy syndromes. So MRI plays a primary role in planning of the treatment, primarily surgical therapy, by detecting structural epileptogenic lesions.

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