Early Colectomy in Severe Ulcerative Colitis

Flatmark, A; Fretheim, B; Gjone, E

doi:10.3109/00365526909180641

Cited by 23 publications

(6 citation statements)

References 6 publications

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Section: Discussionmentioning

confidence: 99%

“…Early colectomy and ileostomy has been historically recommended for the treatment of fulminant or complicated severe UC [8,13] and many studies in the interim have demonstrated its improving safety in the acute situation prior to definitive surgery (see Table 3). Carter et al [6] reported on the complication rates associated with a variety of methods of managing the rectal remnant following total colectomy for UC in 136 patients.…”

Section: Discussionmentioning

confidence: 99%

“…The policy of early surgical intervention and the established role of colectomy and ileostomy in the management of acute severe UC has been widely advocated [7,8] and this has in part resulted in a marked reduction in mortality in the acute setting [9]. Early colectomy with preservation of the rectal stump has been further supported by the poor results achieved in other studies, in which attempts have been made to perform more definitive surgery in the acute setting, including restorative ileo-pouch anal anastomosis (IPAA) [10].…”

Section: Introductionmentioning

confidence: 99%

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Outcomes of the rectal remnant following colectomy for ulcerative colitis

Brady

Collie

et al. 2007

Colorectal Disease

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Outcomes of the rectal remnant following colectomy for ulcerative colitis

Brady

Collie

et al. 2007

Colorectal Disease

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“…In this material there was no change of the remission rate after introduction of parenteral nutrition. Improvement of the colitis on such treatment appears to be the exception rather than the rule (3,4). Nevertheless Solassol et a1 (8) reported that remission was obtained and surgery avoided in 6 out of 12 patients receiving total intravenous nutrition without the addition of steroids.…”

Section: Discussionmentioning

confidence: 99%

Intensive treatment in severe acute attacks of ulcerative colitis

Schjønsby

Heimann

Kremer

et al. 1977

Journal of Internal Medicine

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The results of intensive treatment including steroids and early surgery in severe colitis in the period 1971-1975 were compared to the results from the period 1966-1970, when systematic intensive therapy was not given. The period of preoperative medical treatment was reduced on average from 31 to 17 days. Approximately half the patients went into remission in each period. I n the period 197 1 -1975 (23 patients) there was no mortality during the acute attacks or in the subsequent follow-up period. I n the period 1966-1970, the immediate mortality in 30 patients was 10% (3 patients). One patient died six years later at the age of 81 during a relapse of the colitis, and the overall mortality was 13.3%.

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“…The incidence is \5 %. Early surgical interventions has been shown to decrease the mortality from 22 to 1.2 % [6,7,18]. It is important for clinicians to recognize patients with toxic megacolon in order to refer appropriately.…”

Section: Toxic Megacolonmentioning

confidence: 99%