This review piece, partially compiled by responses to questions from an artificial intelligence (AI) program, ChatGPT, highlights the advantages of AI and machine learning (ML) in investigating and understanding personality and individual differences. Both AI and ML have been shown to be useful tools in fields such as clinical psychology, psychometrics, personality, emotion research, and cognition. In addition to highlighting the advantages of AI and ML in research, the present review also discusses some of the limitations of these new and developing tools.