Early detection of breast cancer using ER specific novel NIR fluorescent dye conjugate: a phantom study using FD-FDOT system

Pillai, Vinay Jha; Jose, Iven; Ramachandran, Hema

doi:10.1117/12.2510169

Cited by 1 publication

(1 citation statement)

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“…Cancer is a major public health problem and the second leading cause of death globally. e latest update from the IARC (International Agency for Reseach on Cancer), the cancer burden rises to 18.1 million new cases and responsible for an estimated 9.6 million deaths in 2018 [1]. However, conventional treatments such as surgery, radiation, chemotherapy, and biologic therapies (immunotherapy) are limited by the accessibility to the tumor, the risk of operating on a vital organ, the spread of cancer cells throughout the body, and the lack of selectivity toward the tumor cells [2].…”

Section: Introductionmentioning

confidence: 99%

Oriented Attachment Crystal Growth Model in Hydrothermal Synthesis of Magnetite (Fe3O4) Nanoparticles

Fadli

Amri

Sari

et al. 2019

J. Appl. Mat. Tech.

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ABST CT: e magnetite nanoparticles (Fe 3 O 4 ) are very promising nanomaterial to be applied as drug delivery due to their excellent superparamagnetic, biocompatibility and easily modified surface properties. ose properties are influenced by the structure and size of the material which depend on the synthesis condition. Studying the evolution of crystal growth can help understand the mechanisms and factors that play a role in it more systematically. e purpose of this research is to study the evolution of crystal growth of magnetite nanoparticles in the hydrothermal system and determine the crystal growth kinetics using the Oriented A achment Growth model. Magnetite nanoparticles were synthesized using a hydrothermal method from FeCl 3 , citrate, urea and polyethylene glycol at 210˚C for 1 -12 hours at a various concentration of FeCl 3 (0.05 M, 0.10 M, and 0.15 M). e characterizations were conducted by X-ray Diffraction (XRD), Transmission Electron Microscope (TEM), Particle size analyzer (PSA), and Vibrating Sample Magnetometer (VSM). e XRD diffractogram indicated that the magnetite was begun to form at 3.5 hours synthesis. e crystallinity and the crystal size of magnetite rose with reaction time. e diameter of magnetite crystals was in the range of 9.4-30 nm. Characterization by TEM showed that the particles were formed from smaller particles which were then agglomerated. e characterization by PSA showed that an increase in FeCl 3 concentration made the particle size larger but the particle distribution narrower. PSA results also prove that the longer the reaction time, the more particle diameter increases will be. VSM result showed that the magnetite nanoparticle has superparamagnetic properties. e magnetite crystal growth can be fi ed by the Oriented A achment Growth model with an error of 29%.

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Section: Introductionmentioning

confidence: 99%