Early detection of unhealthy behaviors, the prevalence and receipt of antiviral treatment for disabled adult hepatitis B and C carriers

Abstract

BackgroundEvidence indicates that hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are the leading causes of liver cirrhosis and hepatocellular carcinoma. Antiviral treatments have recently been reported as successful cures. However, the prevalence rates of HBV or HCV infection, unhealthy behaviors and receipt of adequate treatment in disabled adults have not been described. The aim of this study was to examine the prevalence of HBV or HCV carriers, receipt of antiviral treatment, and early detection of unhealthy behaviors in disabled adults in Taiwan.MethodsA population-based, cross-sectional study was conducted between July and December 2013 with 845 community-dwelling adults with disabilities aged >20 years. Statistical analyses included descriptive statistics, Chi-squared tests, and stepwise regression analysis.ResultsThe prevalence of HBV and HCV infections was 12.9 and 14.1 %, respectively. HCV carriers tended to be older (p < 0.001) and with a lower education (p < 0.001). The majority of HBV/HCV carriers did not know the type of hepatitis infection and did not receive adequate antiviral treatment. After adjusting for potential confounding variables, regression analysis showed that the factors significantly associated with elevated liver function were HCV infection (p < 0.001), HBV infection (p = 0.001), high fasting blood glucose levels (p = 0.001), overweight (p = 0.003), older age (p = 0.027), and alcohol drinking (p = 0.028).ConclusionsThere was a high prevalence of HCV infection among adults with disabilities; few received adequate antiviral treatment or early detection of unhealthy behaviors for the prevention of liver cancer. Clinicians can provide health education to help the participants and caregivers better understand the relationships between specific risk factors and liver health and can encourage HBV and HCV carriers to undergo annual physical check-ups and receive adequate treatment, as covered by the national health insurance.

Effects of oral hygiene programme and home phone counselling for hepatitis C patients receiving antiviral treatment

“…Additionally, many participants were smoking, drinking alcohol, and chewing betel nuts while receiving AVT. The participants' characteristics support the findings of previous studies that most patients with HCV are from a low socioeconomic status and, thus, have poor oral hygiene behaviours (Chang et al, 2015;Jane et al, 2016). The present finding echoed previous studies that men adopt less oral Note.…”

“…Previous studies have indicated that most hepatitis C patients have low socioeconomic backgrounds, which could explain why they have more oral health problems compared with healthy people (Coates et al, 2000;Hayashi et al, 2013;Jane, Chiu, Chen, Lin, & Chen, 2016) and this, in turn, increases their tendency to drop out of the AVT, which lasts for 24-48 weeks (Hepgul et al, 2012;Nagao et al, 2012;Saito et al, 2014).…”

Trend of Disabled Person Care for Establishment of Visiting Health Management Model for the Disabled

“…의과 연구의 경우 단면조사연구가 1편 30) , 비무작위대 조 임상연구 1편 31) , 단일군 전후비교 연구가 2편 32,33) , 후 향적 차트 리뷰 2편 34,35) 이 보고되었다. 증례보고가 1편 36) , 기타 단순 보고서나 문헌고찰이 4편 [37][38][39][40] 이 보고되었다 (Table II).…”

“…(2) 연구자 선정된 연구들에서 13편의 연구가 치과 치료 관련 연 구 [17][18][19][20][21][22][23][24][25][26][27][28][29] 였으며, 나머지 11편은 모두 의과 치료 관련 연구 [30][31][32][33][34][35][36][37][38][39][40] 이었다( Table II).…”

“…( 17,20,26,27,29) , 의과 치료 3편 31,32,39) ), 발달장애 환자에 대한 치과 치료 연구 1편 18) , 신체/정신/감각장애 환자에 대한 치과 치료 연구 1편 19) , 인지장애에 대한 치과 치료 연구 1편 21) , 다 운증후군 등에 대한 치과 치료 연구 1편 22) , 정신지체장 애에 대한 의과 치료 연구 2편 33,38) , 간질(epilepsy) 환자 this study suggest that underlying medical or mental conditions may influence the dental condition and treatment modality provided. www.e-jkmr.org 69 에 대한 의과 치료 연구 2편 34,37) , 뇌성마비(cerebral palsy)에 대한 의과 치료 연구 1편 36) , Phelan-McDermid syn-drome에 대한 연구 1편 40) , 그리고 장애의 종류를 명시 하지 않은 연구 6편(치과 치료 [23][24][25]28) , 의과 치료 30,35) ) 등 다양한 장애 유형에 대한 연구가 보고되었다 (Table II)…”