Early diagnosis and successful treatment of acquired toxoplasmosis infectious retinochoroiditis

Abstract

Rationale:Toxoplasma gondii is distributed worldwide, infecting a large population. It can cause focal necrotic retinitis or retinochoroiditis in the human eyes and is one of the most common causes of posterior uveitis.Patient concerns:A 68-year-old patient with normal immunity was complained about blurred vision and black shadow in the right eye for 1 week.Diagnoses:Combined Yellow-and-white bulged lesions in the fundus of the right eye with the Goldmann-Witmer coefficient = 2 and based on the serological indicators, we considered the diagnosis of T. gondii infection-induced retinochondritis.Interventions:Acetylspiramycin 0.4 QID × 3 weeks, concussive 20 days treatment after 3 days, for a total of 3 months, prednisone 20 mg/day with a weekly reduction of 5 mg for 1 month.Outcomes:After oral acetylspiramycin, topical and systemic corticosteroids for 3 months, the retinal lesions were scarred, and inflammation of the anterior chamber and vitreum disappeared. After a 9-month follow-up, the visual acuity was 0.6, and no active lesions were observed in the fundus.Lessons:The immunocompetent elderly who are in contact with domestic cats may have an opportunistic infection with toxoplasmosis leading to primary retinochoroiditis. Prompt diagnosis and effective treatment can get a good clinical prognosis.

Vitreous Humor Positive for DNA of Human Herpesvirus 7 in Eye With Ocular Toxoplasmosis

“…Based on the ocular signs and a history of previous medications, he was diagnosed with recurrent ocular toxoplasmosis. Because the pre-diagnosis dosage of acetylspiramycin did not appear to be effective, the dose was increased to 1200 mg, and the oral corticosteroid was changed from prednisone to 2 mg of betamethasone [4,5]. One month later, the intraocular pressure had decreased, but the fundus findings had not improved.…”