Early diagnosis of Armanni–Ebstein phenomenon at autopsy

Abstract

A 41-year-old woman with a past history of insulindependent diabetes mellitus, intravenous drug use and asthma was found collapsed and unresponsive at her home address. Her history also included previous hospital admissions with diabetic ketoacidosis. She was conveyed by ambulance to hospital, where she was found to be unconscious, hypotensive and acidotic with a markedly elevated blood glucose level. Resuscitative efforts were unsuccessful.At autopsy, the most significant finding was of marked pallor of both renal cortices on cut section (Fig. 1). Other findings included pulmonary edema with evidence of recent attempts at resuscitation. Fig. 1 Marked pallor of the renal cortex in a 41-year-old woman presenting to hospital unconscious

Alcoholism and the Armanni–Ebstein lesion

“…Neilson, Thomsen and colleagues further examined these lesions and reported that the vacuoles contained fat [4,5]. In 2010 Byard also recorded fat in the lesions and pointed out that a clue to the diagnosis is the macroscopic appearance of the cortex with pallor present [15]. The same appearance may be seen in cases of alcoholic ketoacidosis (Fig.…”

Armanni-Ebstein lesion, ketoacidosis and starvation in a child

“…Thomsen and colleagues reported that the vacuoles in Armanni-Ebstein lesion contained fat [5,6]. In 2010 Byard also recorded fat in the lesions and pointed out that a clue to the diagnosis is the macroscopic appearance of the cortex with pallor present [7].…”

Erosive gastritis, Armanni-Ebstein phenomenon and diabetic ketoacidosis

“…In the reported case significant tubular vacuolization was present, to such an extent that it was first identified macroscopically [13], and this was associated with Wischnewsky spots indicating hypothermia. Diabetic ketoacidosis was, however, subsequently identified biochemically by testing of vitreous humor for glucose, lactate and b-hydroxybutyrate.…”