Early Diagnosis of Cutaneous Melanoma

Abbasi, Naheed R.; Shaw, Helen M.; Rigel, Darrell S.; Friedman, Robert J.; McCarthy, William H.; Osman, Iman; Kopf, Alfred W.; Polsky, David

doi:10.1001/jama.292.22.2771

Cited by 570 publications

(355 citation statements)

References 35 publications

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“…19 The addition of an ''E'' for ''evolving'' to the ABCD system may improve and enhance early recognition by clinicians and laypersons. 20 We advocate the expansion of current preventive educational reminders to the elderly as well as to their immediate environment. Investigations aiming to clarify early features of melanoma in the elderly and promotion of these features to the population and to primary care practitioners would be valuable in secondary prevention of melanoma in the older ages.…”

Section: Discussionmentioning

confidence: 99%

Age and gender are significant independent predictors of survival in primary cutaneous melanoma

Lasithiotakis¹,

Leiter²,

Meier³

et al. 2008

Cancer

229

178

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BACKGROUNDThe aim was to identify age‐ related and gender‐related differences in the clinical presentation and outcome of patients with primary cutaneous melanoma (CM).METHODSA total of 4785 CM patients without clinical evidence of metastasis diagnosed during the period 1976–2001 in southern Germany included in the analysis. Kaplan‐Meier analyses were performed to estimate and to compare disease‐specific survival (DSS) and survival after first recurrence (SAR). The Cox proportional hazards model was used to evaluate the effect of multiple variables on DSS and SAR.RESULTSIncreasing age and male gender were independently associated with thicker tumors (>2 mm) and histologic ulceration (P < .001). Patients older than 65 years had lower 10‐year DSS than younger patients (81.8% vs 88.4%, P < .001) and this difference was more pronounced in women (P < .001) than in men (P = .06). Males had lower 10‐year DSS than females (83.5% vs 88.5%, P < .001) but this difference did not reach statistical significance in patients older than 65 years (P = .162). In multivariate analysis adjusted for tumor thickness, ulceration, anatomic site, histologic subtype, DSS, site of first recurrence, time trend, sentinel lymph node status, age, and gender were independent predictors of DSS and SAR (P < .05).CONCLUSIONSOlder age and male gender are associated with prognostically unfavorable primary CM. Expansion of current preventive strategies to target these subgroups is warranted. Moreover, age and gender are independent predictors of the outcome of CM patients. Females have a better prognosis than males but this difference disappears after the age of 65. Younger patients have a more favorable prognosis than older patients, a difference more pronounced in women. Cancer 2008. © 2008 American Cancer Society.

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Section: Discussionmentioning

confidence: 99%

Age and gender are significant independent predictors of survival in primary cutaneous melanoma

Lasithiotakis¹,

Leiter²,

Meier³

et al. 2008

Cancer

229

178

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“…The symptoms of melanoma usually are detected visually (Abbasi et al, 2004). A lesion is considered to be suspicious if it is laterally asymmetrical in shape, irregular in border, variegated in color, and/or 6 mm or larger in diameter (Bono et al, 1999;Thomas et al, 1998).…”

mentioning

confidence: 99%

Using Morphed Images to Study Visual Detection of Cutaneous Melanoma Symptom Evolution

et al. 2011

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“…Such an analysis provides the opportunity to enlarge the standard ABCD rule [4] or 7-point checklist [5] and involve additional criteria in suspicious skin tissues inspection. For example, dermatoscopy analysis may include monitoring of more specifically related tumor features like atypical pigmentation and vascular networks as well as so-called blue-whitish veil, which represents a gray-white pattern with well perceptible blue tone [6].…”

Section: Introductionmentioning

confidence: 99%

In vivo hyperspectral imaging of skin malignant and benign tumors in visible spectrum

Bratchenko

Sherendak

Myakinin

et al. 2018

JBPE

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Abstract. The paper presents analysis of hyperspectral images for human skin cancer pathologies diagnostics. Hyperspectral images data contained backscattered spectra of normal skin and tumors. Analysis of hyperspectral images provided information about hemoglobin and melanin content for the differentiation of malignant and benign skin neoplasms based on tissues optical density calculation. It was shown that the accuracy of cancerous tissues classification reaches 88% for proposed algorithm of hyperspectral images analysis. The proposed approach may be a rapid and reliable tool for skin oncological diseases screening. © 2018 Journal of Biomedical Photonics & Engineering.Keywords: hyperspectral imaging; backscattering spectroscopy; oncodermatology; oncological diagnostics; melanoma; nevi; carcinoma; melanin; hemoglobin content.

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Early Diagnosis of Cutaneous Melanoma

Cited by 570 publications

References 35 publications

Age and gender are significant independent predictors of survival in primary cutaneous melanoma

Age and gender are significant independent predictors of survival in primary cutaneous melanoma

Using Morphed Images to Study Visual Detection of Cutaneous Melanoma Symptom Evolution

In vivo hyperspectral imaging of skin malignant and benign tumors in visible spectrum

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