Early diagnosis of HIV/aids infection: concept analysis

Abstract

Objectives: to analyze the concept of “early diagnosis of HIV/Aids infection” in light of Walker and Avant’s conceptual analysis model. Methods: concept analysis study based on the framework proposed by Walker and Avant, instrumented by a scoping review conducted in April 2022, following the recommendations of the Joanna Briggs Institute and checklist Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. The search was made in eight data sources, obtaining sixteen articles. Results: the study found homosexual intercourses, early examination, anti-HIV antibodies, CD4 count, and sexually transmitted infection as the main attributes of the concept. As antecedents: information, risky behavior, unprotected sexual relations, prevention, and access to the service. As main consequences: antiretroviral treatment, seroconversion, transmission, and consultations. Final Considerations: the study approached the circumstantial situations of the theme, its attributes, antecedents, and consequences, qualifying the work process based on knowledge of nursing practice.

Identification of a circulating long non-coding RNA signature panel in plasma as a novel biomarker for the detection of acute/early-stage HIV-1 infection

“…The putative viral biomarkers suggested for identifying acute HIV-1 infection have significant limitations because roughly 3–5% of HIV-positive individuals will have a negative RNA test result during the window period of their HIV infection [ 43 ]. A crucial part of reducing HIV-1 transmission is now recognized as being the early detection of recently acquired infections [ 46 ]. Modeling results indicate that up to 50% of adult HIV-1 infections are acquired from patients with acute or early HIV-1 infection [ 47 , 48 ].…”