Early diagnosis of melanoma: what is the impact of dermoscopy?

Argenziano, Giuseppe; Albertini, Giuseppe; Castagnetti, Fabio; Pace, Barbara De; Lernia, Vito Di; Longo, Caterina; Pellacani, Giovanni; Piana, Simonetta; Ricci, Cinzia; Zalaudek, Iris

doi:10.1111/j.1529-8019.2012.01482.x

Cited by 61 publications

(61 citation statements)

References 29 publications

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“…As a main example, it is possible that patients who consulted dermatologists adequately trained in dermoscopy were more careful with their moles and consulted faster when a lesion had appeared or changed. Dermoscopists are also often more motivated to perform total body examinations [26]. Second, the cohorts included in the MDM are rather small and the costs are estimated on a sub-optimal number of patients.…”

Section: Periodsmentioning

confidence: 99%

Cost-effectiveness analysis in melanoma detection: A transition model applied to dermoscopy

Tromme

Legrand

Devleesschauwer

et al. 2016

European Journal of Cancer

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Aim: The main aim of this study is to demonstrate how our melanoma disease model (MDM) can be used for cost-effectiveness analyses (CEAs) in the melanoma detection field. In particular, we used the data of two cohorts of Belgian melanoma patients to investigate the cost-effectiveness of dermoscopy. Methods: A MDM, previously constructed to calculate the melanoma burden, was slightly modified to be suitable for CEAs. Two cohorts of patients entered into the model to calculate morbidity, mortality and costs. These cohorts were constituted by melanoma patients diagnosed by dermatologists adequately, or not adequately, trained in dermoscopy. Effectiveness and costs were calculated for each cohort and compared. Effectiveness was expressed in (2016) 38e45 quality-adjusted life years (QALYs), a composite measure depending on melanoma-related morbidity and mortality. Costs included costs of treatment and follow-up as well as costs of detection in non-melanoma patients and costs of excision and pathology of benign lesions excised to rule out melanoma. Results: The result of our analysis concluded that melanoma diagnosis by dermatologists adequately trained in dermoscopy resulted in both a gain of QALYs (less morbidity and/or mortality) and a reduction in costs. Conclusion: This study demonstrates how our MDM can be used in CEAs in the melanoma detection field. The model and the methodology suggested in this paper were applied to two cohorts of Belgian melanoma patients. Their analysis concluded that adequate dermoscopy training is cost-effective. The results should be confirmed by a large-scale randomised study. ª

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Section: Periodsmentioning

confidence: 99%

Cost-effectiveness analysis in melanoma detection: A transition model applied to dermoscopy

Tromme

Legrand

Devleesschauwer

et al. 2016

European Journal of Cancer

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“…These are: the pattern analysis by Pehamberger, the ABCD rule by Stolz, the ABC rule modified by Kittler, the Menzies method, the seven-point checklist by Argenziano, the CASH algorithm and other. 4,6,15,16 Figures 1 and 2 show typical dermoscopy features of thin versus thick melanomas. The images were taken with a digital dermoscope (videodermoscope).…”

Section: Dermoscopic Features In the Diagnosis Of Different Types Of mentioning

confidence: 99%

“…Additional diagnostic techniques, such as videodermoscopy, ultrasonography or reflectance confocal microscopy usually are used after a preselection by the specialist or on the basis of dermoscopy examination. 6,7 The examination of all pigmented skin lesions, not only lesions preselected by the patient or the clinician is important for several reasons. Patients are usually concerned about palpable skin lesions, including seborrheic keratoses or dermatofibromas, and ignoring small, flat melanocytic lesions, which may be early melanomas.…”

Section: Dermoscopic Features In the Diagnosis Of Different Types Of mentioning

confidence: 99%

“…For GPs a desirable NNE is 20-40, for physicians practicing in primary care skin cancer clinics is 19-28, for dermatologists: 4-18. 6,9 On the basis of the observation that in adult patients benign lesions remain stable whereas melanoma tends to grow and change over time, digital follow-up of melanocytic lesions has been proposed as a strategy to recognize melanoma. Stratification of the risk of developing melanoma is of great importance to establish the best strategies and followup methods.…”

Section: Dermoscopic Features In the Diagnosis Of Different Types Of mentioning

confidence: 99%

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Modern non-invasive diagnostic techniques in the detection of early cutaneous melanoma

Kardynał¹,

Olszewska

2014

J Dermatol Case Rep

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Over the past few years melanoma has grown into a disease of socio-economic importance due to the increasing incidence and persistently high mortality rates. Melanoma is a malignant tumor with a high tendency to metastasize. Therefore, an extremely important part of the therapeutic process is to identify the disease at an early stage: in situ or stage I. Many tools for early diagnosis of melanoma are available today, including dermoscopy, videodermoscopy and in vivo reflectance confocal microscopy. Other methods such as high frequency ultrasound, optical coherence tomography and electrical impedance spectroscopy may serve as additional diagnostic aids. Modern imaging techniques also allow the monitoring of melanocytic skin lesions over months or years to detect the moment of malignant transformation. This review summarizes the current knowledge about modern diagnostic techniques, which may aid early diagnosis of

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“…22 It may be noted that the NNE generally varies from 20-40 for primary care clinicians in non-specialized clinics, and 4-18 for dermatologists at specialty clinics. 23 A multinational, multicenter prospective trial recruited 14,381 subjects from all willing adult patients seeking dermatology consultation for focused skin lesions. As a result, a TBSE was initiated for each participant and suspicious or equivocal lesions were excised or biopsied.…”

Section: Recent Evidence Regarding Screeningmentioning

confidence: 99%

Primary Care for Melanoma: Should We Be Screaming for Screening?

Baumgardner¹,

Rogers²

2014

Journal of Patient-Centered Research and Reviews

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Follow this and additional works at: https://aurora.org/jpcrr Part of the Oncology CommonsJournal of Patient-Centered Research and Reviews ( JPCRR) is a peerreviewed scientific journal whose mission is to communicate clinical and bench research findings, with the goal of improving the quality of human health, the care of the individual patient, and the care of populations. Recommended CitationBaumgardner DJ, Rogers A. Primary care for melanoma: should we be screaming for screening?. J Patient Cent Res Rev. 2014;1:33-40. doi: 10.17294/2330-0698.1009 Aurora.org/Journal 33 AbstractThe incidence of cutaneous malignant melanoma continues to rise in the United States. This deadly disease is potentially curable if caught at an early stage, however screening programs remain controversial. The United States Preventive Services Task Force cites insufficient evidence to recommend screening, by total-body skin examination (TBSE), for early detection of cutaneous melanoma. While definitive studies may be cost-prohibitive in the United States, more recent evidence suggests that organized programs to increase TBSE reduce mortality from melanoma. The positive impact of TBSE, and education regarding risk reduction and skin selfexamination, is most likely to be cost-effective in high-risk patients such as middle-aged and older men. This population also includes those with changing moles or those who always or usually sunburn; those with melanoma in a first-degree relative, or dysplastic nevi or extensive moles; and those with high-risk ultraviolet (UV) exposure or other risk factors. The role of new technology, such as in-office and in-home dermoscopy, continues to evolve. Primary care clinicians are challenged in everyday practice to appropriately prioritize TBSE and empower their patients for "skin awareness" and self-detection of melanoma. (J Patient-Centered Res Rev.

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Early diagnosis of melanoma: what is the impact of dermoscopy?

Cited by 61 publications

References 29 publications

Cost-effectiveness analysis in melanoma detection: A transition model applied to dermoscopy

Cost-effectiveness analysis in melanoma detection: A transition model applied to dermoscopy

Modern non-invasive diagnostic techniques in the detection of early cutaneous melanoma

Primary Care for Melanoma: Should We Be Screaming for Screening?

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