“…The purpose is to describe any changes in cardiac status that occurred, to relate them to recurrences and the total number of attacks, and to show to what extent, if any, they were affected by treatment with hormone or salicylates, or by prophylaxis. Previously we had found that drug therapy was only occasionally of more benefit than bed rest alone in the acute phase of the disease (Bywaters and Thomas, 1961) and that prophylaxis was effective in reducing the number of recurrences in this country (Bywaters and Thomas, 1958), as had been the experience in the U.S.A. (Thomas and France, 1939).…”