EARLY EFFECTS OF SODIUM IODATE ON THE SLOW OFF‐EFFECTS, PARTICULARLY THE h‐WAVE, AND ON THE c‐WAVE OF THE DC RECORDED ELECTRORETINOGRAM IN RABBIT

Abstract

The early effects of intravenously administered sodium iodate (NaIO3) on the slow, negative 'off-effect', the h-wave, and on the slow, positive 'on-effect', the c-wave, of the DC recorded electroretinogram were studied in 8 rabbits. Both the h- and c-waves disappeared gradually after NaIO3 administration and were replaced by potentials of opposite polarity. These results strongly support the assumption that the h-wave originates in the pigment epithelium and represents the reversal of events underlying the c-wave. The slow, positive 'off-effect', the g-wave, elicited by 'dark flashes' was seen to pass into the potential replacing the h-wave after NaIO3 treatment.