2004
DOI: 10.1016/j.clnu.2004.03.010
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Early enteral gut feeding with conditionally indispensable pharmaconutrients is metabolically safe and is well tolerated in postoperative cancer patients?a pilot study*1

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Cited by 18 publications
(8 citation statements)
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“…Plasma glutamine levels did not increase after 7 days in any of the groups, while duodenal mucosal glutamine concentration only increased in the patients fed the glutamine-rich protein feed. In two small pilot studies in which glutamine dipeptide was given jejunally in the form of Intestamin to patients after gastrointestinal cancer surgery, plasma glutamine levels increased in one study (45) but not the other (46). In a recent dose-finding pilot study using glutamine and antioxidants in ventilated critically ill patients with evidence of hypoperfusion, Heyland and colleagues (47) combined intravenous glutamine (Dipeptiven) with enteral glutamine as Intestamin and demonstrated normalization in plasma glutamine levels, but the small size of this study (seven patients per dosage group) makes it difficult to separate the relative contributions of the intravenous and enteral components.…”
Section: Discussionmentioning
confidence: 97%
“…Plasma glutamine levels did not increase after 7 days in any of the groups, while duodenal mucosal glutamine concentration only increased in the patients fed the glutamine-rich protein feed. In two small pilot studies in which glutamine dipeptide was given jejunally in the form of Intestamin to patients after gastrointestinal cancer surgery, plasma glutamine levels increased in one study (45) but not the other (46). In a recent dose-finding pilot study using glutamine and antioxidants in ventilated critically ill patients with evidence of hypoperfusion, Heyland and colleagues (47) combined intravenous glutamine (Dipeptiven) with enteral glutamine as Intestamin and demonstrated normalization in plasma glutamine levels, but the small size of this study (seven patients per dosage group) makes it difficult to separate the relative contributions of the intravenous and enteral components.…”
Section: Discussionmentioning
confidence: 97%
“…La jéjunostomie et les sondes transanastomotiques en chirurgie digestive haute (gastrectomie partielle et anastomose gastrojéjunale, chirurgie de l'oesophage, chirurgie du bloc duodénopancréatique) [28,29] permettent une NEP postopératoire.…”
Section: Court-circuiter L'estomac Et Le Pylore 4321 Dans Un Contunclassified
“…Em estudo prospectivo randomizado realizado por Aguilar-Nascimento et al 38 , verificou-se que não houve diferença significante entre as taxas de deiscência de anastomose entre o grupo que recebeu nutrição precoce e o submetido a tratamento convencional. A nutrição precoce é viável e segura, mesmo quando oferecida entre quatro a 12 horas após a operação [34][35][36][37][38][39][40][41] . Na verdade, a oferta precoce de nutrientes estimula reflexo que produz atividade propulsiva coordenada e, induz à secreção de hormônios gastrointestinais, diminuindo por conseguinte o íleo pós-operatório.…”
Section: Correia Et Alunclassified