2009
DOI: 10.1007/s11605-008-0592-x
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Early Enteral Nutrition Within 24 h of Intestinal Surgery Versus Later Commencement of Feeding: A Systematic review and Meta-analysis

Abstract: There is no obvious advantage in keeping patients 'nil by mouth' following gastrointestinal surgery. Early enteral nutrition is associated with reduced mortality, though the mechanism is not clear. This review supports the notion that early commencement of enteral feeding may be of benefit.

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Cited by 416 publications
(281 citation statements)
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“…Early recommencement of post‐operative nutrition has been shown to benefit the patient 52. However, most of the available data are from patients undergoing surgery in a traditional care programme, and very little is known about the effects of nutrition in a modern ERAS programme.…”
Section: Metabolic Homoeostasismentioning
confidence: 99%
“…Early recommencement of post‐operative nutrition has been shown to benefit the patient 52. However, most of the available data are from patients undergoing surgery in a traditional care programme, and very little is known about the effects of nutrition in a modern ERAS programme.…”
Section: Metabolic Homoeostasismentioning
confidence: 99%
“…In addition, early postoperative oral feeding has been shown to be feasible in patients undergoing major surgery, and no side effects have been reported. 53 The physiological advantage of feeding at a time of catabolic stress relates to the increased stimulation of insulin production that subsequently inhibits the breakdown of protein. This then facilitates incorporation of the amino acids -made available by the feeding -into protein synthesis.…”
Section: Perioperative Feedingmentioning
confidence: 99%
“…A Cochrane review in 2006 found a direction of effect towards a reduction in complications and mortality rate, 65 and in an update to their original metanalysis, Lewis and colleagues confirmed no benefit to keeping patients nothing by mouth (NBM) postoperatively, a reduction in complications and a reduced mortality rate; although, the mechanism for reduced mortality remains unclear. 66 …”
Section: Postoperative Nutritionmentioning
confidence: 99%