Early estimation of the case fatality rate of COVID-19 in mainland China: a data-driven analysis

Yang, Shu; Cao, Peihua; Du, Peng; Wu, Ziting; Zhuang, Zian; Yang, Lin; Yu, Xuan; Zhou, Qi; Feng, Xiangyu; Wang, Xiaohui; Li, Weiguo; Liu, Enmei; Chen, Ju; Chen, Yaolong; He, Daihai

doi:10.21037/atm.2020.02.66

Cited by 174 publications

(162 citation statements)

References 15 publications

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“…Although data surrounding the novel coronavirus are rapidly evolving, initial estimates depict a dire situation: 20% of infections lead to severe or critical disease [2]. Mortality has varied across settings, but early data suggest a case fatality rate near 4% [4,5].…”

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confidence: 99%

WITHDRAWN: COVID-19 Severity Scoring Tool for low resourced settings

Wallis

2020

African Journal of Emergency Medicine

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confidence: 99%

WITHDRAWN: COVID-19 Severity Scoring Tool for low resourced settings

Wallis

2020

African Journal of Emergency Medicine

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“…The survey instrument was developed using an iterative process, based on a thorough review of the literature surrounding COVID-19, [21][22][23][24][25] and discussions with transplant surgeons and transplant ID physicians. The final survey was approved by two transplant surgeons and two transplant ID physicians with input from members of the transplant team (Supplement).…”

Section: Survey Designmentioning

confidence: 99%

Early impact of COVID-19 on transplant center practices and policies in the United States

Boyarsky

Chiang

Werbel

et al. 2020

American Journal of Transplantation

228

276

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COVID-19 is a novel, rapidly changing pandemic: consequently, evidence-based recommendations in solid organ transplantation (SOT) remain challenging and unclear. To understand the impact on transplant activity across the United States, and center-level variation in testing, clinical practice, and policies, we conducted a national survey between March 24, 2020 and March 31, 2020 and linked responses to the COVID-19 incidence map. Response rate was a very high 79.3%, reflecting a strong national priority to better understand COVID-19. Complete suspension of live donor kidney transplantation was reported by 71.8% and live donor liver by 67.7%.While complete suspension of deceased donor transplantation was less frequent, some restrictions to deceased donor kidney transplantation were reported by 84.0% and deceased donor liver by 73.3%; more stringent restrictions were associated with higher regional incidence of COVID-19. Shortage of COVID-19 tests was reported by 42.5%. Respondents reported a total of 148 COVID-19 recipients from <1 to >10 years posttransplant: 69.6% were kidney recipients, and 25.0% were critically ill. Hydroxychloroquine (HCQ) was used by 78.1% of respondents; azithromycin by 46.9%; tocilizumab by 31.3%, and remdesivir by 25.0%. There is wide heterogeneity in center-level response across the United States; ongoing national data collection, expert discussion, and clinical studies are critical to informing evidence-based practices. K E Y W O R D Sclinical decision-making, epidemiology, guidelines, infectious agents-viral

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“…Moreover, the presence of comorbidities such as diabetes or cardiovascular or respiratory disorders greatly affects outcome. Indeed, being elderly or having a delay in diagnosis were found to substantially increase the case-fatality rate [10,11].…”

Section: Introductionmentioning

confidence: 99%

Epidemiology, genome, and clinical features of the pandemic SARS-CoV-2: a recent view

Abduljalil

2020

New Microbes and New Infections

129

126

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Since the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, the number of globally confirmed cases according to World Health Organization statistics reached 292 124 in 189 countries by 22 March 2020. The number of deaths reached 12 784, with estimated case-fatality rates ranging from 0.5% to 5.7%. Children population seems to be the least affected by the disease, while the highest rate of death is among the elderly and people with comorbidities. Most infected individuals are asymptomatic or only exhibit mild symptoms. After the incubation period, the most common symptoms are fever, cough and fatigue.Asymptomatic carrier state is of paramount importance because of carriers' ability to spread the infection and to shed the virus into the air and surroundings. Although much is still unknown about SARS-CoV-2, the scientific research is moving at an unprecedented pace towards understanding the nature, effective control, prevention and treatment of SARS-CoV-2. Various reports have suggested an in vivo evolution of the virus, which may explain the rapid spread and changing epidemiology of SARS-CoV-2, but further evidence is needed.Unfortunately, no effective treatment or therapeutic drug is available for the disease; only supportive treatment and classical intervention measures are available for confronting the SARS-CoV-2 pandemic.

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Early estimation of the case fatality rate of COVID-19 in mainland China: a data-driven analysis

Cited by 174 publications

References 15 publications

WITHDRAWN: COVID-19 Severity Scoring Tool for low resourced settings

WITHDRAWN: COVID-19 Severity Scoring Tool for low resourced settings

Early impact of COVID-19 on transplant center practices and policies in the United States

Epidemiology, genome, and clinical features of the pandemic SARS-CoV-2: a recent view

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