Early extubation after lung transplantation

Intraoperative Implications of the Recipients' Disease for Double-Lung Transplantation

“…30 Despite the call for randomized trials by Myles et al., no study on ultrafast-track or immediate extubation after lung transplantation has been published. 31 Two cohorts have been reported more recently: one of CF patients by Felten et al in 2016 32 and one of COPD patients by Assenzo et al in 2018. 33 Both studies reported the feasibility of immediate extubation "in the operating room" in approximately half of the patients, and pulmonary graft dysfunction and one-year mortality were relatively better in COPD patients.…”

Operating room extubation: A predictive factor for 1-year survival after double-lung transplantation

“…However, our team has routinely adopted an OR extubation strategy according to the following fundamental practices: the use of short-acting drugs combined with effective analgesia, such as thoracic epidural analgesia; the avoidance of excessive fluid support; the maintenance of normothermia; and the application of systematic postoperative noninvasive ventilation. 9 Our group published an OR extubation strategy based on data from two separate cohorts considering specific populations: cystic fibrosis patients 10 and emphysema or chronic obstructive pulmonary disease (COPD) patients. 11 The main objective of the present study was to predict the prognosis of patients extubated immediately by comparing it with the prognosis of patients extubated in the ICU.…”