Early follow‐up of lung disease in infants with cystic fibrosis using the raised volume rapid thoracic compression technique and computed tomography during quiet breathing

Abstract

All RVRTC parameters and the CTqb score remained stable between evaluations. The CTqb score showed a higher discriminative power than forced expiratory volume in 0.5 s (FEV ; the main RVRTC parameter) at both visits (66% and 50% of abnormal values vs 30% and 28%, respectively). No correlation was found between CTqb score and the different RVRTC parameters or the plethysmographic functional residual capacity, indicating that they evaluate different aspect of CF lung disease.

Cystic fibrosis year in review 2017

“…Raised volume‐rapid thoracic compression (RVRTC) is a promising tool for evaluation of respiratory tract disease in infants with CF, but the need of sedation and positive pressure ventilation limits its clinical use. An alternative, semi‐quantitative method to evaluate air trapping by chest tomography during quiet breathing without sedation (CTqb score), allows assessment of airway obstruction and could be useful for longitudinal evaluation of lung disease in CF infants . To compare the discriminative powers of, and determine correlation between, the CTqb score and RVRTC parameters, a multicenter longitudinal study enrolled infants with CF diagnosed by NBS.…”

Pediatric Pulmonology year in review 2017: Part 3

“…45 thoracic compression technique at 10 weeks and 13 months of age. 46 They determined that chest CT obtained during quiet breathing showed a higher discriminative power than forced expiratory volume in 0.5 s (FEV 0.5 ) in evaluating lung disease. However, there was no correlation between chest CT findings and FEV 0.5 , suggesting that these tests evaluate different aspects of early CF lung disease.…”

“…Pulmonary function in CF is known to be abnormal early in life, but assessment of lung function in CF infants is difficult. Gauthier et al evaluated the discriminative power between unsedated chest computed tomography (CT) during quiet breathing and infant pulmonary function testing performed with the raised volume rapid thoracic compression technique at 10 weeks and 13 months of age . They determined that chest CT obtained during quiet breathing showed a higher discriminative power than forced expiratory volume in 0.5 s (FEV 0.5 ) in evaluating lung disease.…”

Eficácia da técnica de compressão torácica durante a avaliação da função pulmonar em lactentes: uma revisão sistemática

“…A alteração da função pulmonar em lactentes, traz consequências comprometendo o padrão respiratório, fazendo que tenha a necessidade de recrutar músculos acessórios da respiração e estabilidade da cintura escapular, para a manutenção da troca gasosa (Scavacini et al, 2020). Os recém-nascidos que apresentam displasia broncopulmonar ou síndrome do desconforto respiratório que são submetidos ao uso de ventilação mecânica podem apresentar algumas alterações na função pulmonar (Gauthier et al, 2017).…”