Early gastric carcinoma: spread and multicentricity

Huguier, M; Ferro, Leonardo; Barrier, Alain

doi:10.1007/s101200200022

Cited by 17 publications

(10 citation statements)

References 26 publications

(38 reference statements)

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“…Takeshita found a higher incidence of depressed macroscopic type in his series of 61 MEGCs, 7 while Huguier observed a high number of nondifferentiated histologic type EGCs in his relatively small patient population. 12 Genetic factors such as germline mutations in the E-caderin gene have also been reported to be involved in a small number of signet ring cell diffuse histotype EGCs with multiple foci. 13,14 Twenty-nine of our patients presented diffuse carcinoma, but as no hereditary cancers were hypothesized, genetic studies were not conducted.…”

Section: Discussionmentioning

confidence: 99%

Subtotal Gastrectomy as Treatment for Distal Multifocal Early Gastric Cancer

Morgagni

Marfisi

Gardini

et al. 2009

Journal of Gastrointestinal Surgery

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Section: Discussionmentioning

confidence: 99%

Subtotal Gastrectomy as Treatment for Distal Multifocal Early Gastric Cancer

Morgagni

Marfisi

Gardini

et al. 2009

Journal of Gastrointestinal Surgery

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“…For early gastric cancer, the five-year survival rate after successful surgical resection is over 90% 12. The frequency of recurrent cancer in the gastric remnant after distal gastrectomy is around 1-5%,5,13 and it is known that 20% of the patients who died from the recurrence of gastric cancer had recurrent cancer that was limited to the gastric remnant 14. The risk of recurrent cancer in the gastric remnant is known to be proportional to the amount of time after the operation.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for Food Residue after Distal Gastrectomy and a New Effective Preparation for Endoscopy: The Water-Intake Method

Cho¹,

Yoon²,

Park³

et al. 2009

Gut Liver

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Background/AimsFood residue is frequently observed in the gastric remnant after distal gastrectomy, despite adequate preparation. We devised a water-intake method to reduce food residue in the gastric remnant by drinking large quantities of water in a short time. The aims of this study were to identify the risk factors for food residue and to study the effectiveness of this new method for endoscopy preparation.MethodsA cohort of 708 patients who underwent distal gastrectomy for gastric cancer was reviewed prospectively. Sixty patients with large amounts of food residue were randomly divided into two groups: a water-intake group (n=40) and a prolonged fasting group (n=20).ResultsThe incidences of a large amount of food residue were 15.7%, 5.8%, 7.5%, and 2.8% at 3, 12, 24, and 36 months, respectively, after distal gastrectomy. Independent risk factors for food residue were endoscopy at 3 months, diabetes mellitus, a body mass index of <19.5, and laparoscopic surgery. The proportion of successful preparations at follow-up endoscopy was higher for the water-intake group (70%) than for the prolonged fasting group (40%, p=0.025).ConclusionsThe water-intake method can be recommended as a preparation for endoscopy in patients who have had repetitive food residue or risk factors after distal gastrectomy.

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“…Multiple cancers occur in patients with early gastric cancer at a frequency of 2.07-21 % [2][3][4][5][6][7][8], and multiple cancers are common in elderly patients with differentiated-type lesions [3,5,9,10]. Further, multiple cancers often occur in the same background mucosa [2,5].…”

Section: Discussionmentioning

confidence: 99%

Simple pathological examination technique for detection of cancer located at the surgical margin of the stomach

et al. 2013

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Background The technique for examining surgical resection margins described in the Japanese Classification of Gastric Carcinoma is based on the examination of continuous infiltration by the primary tumor, and discontinuous lesions such as multiple cancers are not examined. However, examining lesions-particularly cancers-at the resection margins is important for the prevention of cancers in the remaining stomach that result from cancer remnants (remnant gastric cancer). Methods The clinical usefulness of a simple pathological examination technique for detecting cancer located at the surgical margin of the stomach was studied. A specimen 5-8 mm wide was resected from the surgical cut margin along the entire circumference of the stomach. When the pathological margin was positive for cancer, the surgical margin was also examined, and cases that were positive for cancer were regarded as marginally positive.Results Of the 1,498 patients with early gastric cancer who were examined using this method, 17 (1.1 %) were marginally positive for multiple cancers, and 8 of these 17 patients (57 %) had microcancers \5 mm in diameter. Conclusion This method is simple and useful for detecting cancer involving the surgical margin, which occurs at a rate of 1.1 %, making it possible to prevent remnant gastric cancer by reoperation.

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Early gastric carcinoma: spread and multicentricity

Cited by 17 publications

References 26 publications

Subtotal Gastrectomy as Treatment for Distal Multifocal Early Gastric Cancer

Subtotal Gastrectomy as Treatment for Distal Multifocal Early Gastric Cancer

Risk Factors for Food Residue after Distal Gastrectomy and a New Effective Preparation for Endoscopy: The Water-Intake Method

Simple pathological examination technique for detection of cancer located at the surgical margin of the stomach

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