Early Hemodynamics after Aortic Valve Replacement

Aitaliyev, Serik; Rumbinaitė, Egle; Mėlinytė-Ankudavičė, Karolina; Nekrošius, Rokas; Keturakis, Vytenis; Benetis, Rimantas

doi:10.3390/medicina56120674

Cited by 2 publications

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References 27 publications

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“…In our previous paper, we detected a PPM rate of 9.5% using the continuity equation. 27 We speculate that the low PPM rate might be related to the excellent hemodynamic conditions of the St. Jude Trifecta (>70%) in our study. Several studies presented favourable hemodynamics with St. Jude Trifecta in the AV position and considered it as the best option for AVR surgery.…”

Section: Discussionmentioning

confidence: 62%

Early outcomes of patient-prosthesis mismatch following aortic valve replacement

et al. 2021

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Introduction: Patient-prosthesis mismatch (PPM) has been associated with numerous short- and long-term adverse events. This study aimed to evaluate the effect of PPM on early postoperative results after aortic valve replacement (AVR) in daily practice. Methods: In this single-centre retrospective study, 150 non-consecutive patients from March 2019 to January 2020 with clinically indicated AVR with/without concomitant surgery were analysed. The study protocol included operative mortality, complication rate, and pre- and postoperative echocardiographic data. PPM was considered severe with indexed effective orifice area at <0.65 cm2/m2, moderate at 0.65–0.85 cm2/m2 and none at >0.85 cm2/m2. Results: Moderate PPM was observed in 16 patients (10.6%). No patient had severe PPM. PPM was not related to early mortality ( r = 0.40, p = 0.630), intra- ( r = −0.076, p = 0.352) and postoperative ( r = −0.0134, p = 0.102) events. Conclusion: In this study, moderate PPM was a frequent finding after AVR, whereas severe PPM was not observed. PPM did not affect the early results after AVR. A long-term follow-up study in a large patient population is required to assess the actual influence of residual PPM.

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Section: Discussionmentioning

confidence: 62%

Early outcomes of patient-prosthesis mismatch following aortic valve replacement

et al. 2021

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“…In a single-center, prospective trial, 116 patients underwent AVR with/without concomitant surgery. This cohort and surgical techniques were described previously [10,11]. The study population was divided into isolated aortic stenosis (isolated AS) and aortic stenosis with the ischemic heart diseases (AS+IHD) groups.…”

Section: Methodsmentioning

confidence: 99%

Histologically Validated Myocardial Fibrosis in Relation to Left Ventricular Geometry and Its Function in Aortic Stenosis

Aitaliyev,

Rumbinaitė,

Jurenas

et al. 2024

Medicina

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Background and Objectives: The combination of aortic valve stenosis (AS) and ischemic heart disease (IHD) is quite common and is associated with myocardial fibrosis (MF). The purpose of this study was to evaluate the association between the histologically verified left ventricular (LV) MF and its geometry and function in isolated AS and AS within IHD groups. Materials and Methods: In a single-center, prospective trial, 116 patients underwent aortic valve replacement (AVR) with/without concomitant surgery. The study population was divided into groups of isolated AS with/without IHD. Echocardiography was used, and LV measurements and aortic valve parameters were obtained from all patients. Myocardial tissue was procured from all study patients undergoing elective surgery. Results: There were no statistical differences between isolated AS and AS+IHD groups in LV parameters or systolic and diastolic functions during the study periods. The collagen volume fraction was significantly different between the isolated AS and AS+IHD groups and was 7.3 ± 5.6 and 8.3 ± 6.4, respectively. Correlations between MF and left ventricular end-diastolic diameter (LVEDD) (r = 0.59, p = < 0.001), left ventricular mass (LVM) (r = 0.42, p = 0.011), left ventricular ejection fraction (LVEF) (r = −0.67, p < 0.001) and an efficient orifice area (EOA) (r = 0.371, p = 0.028) were detected in isolated AS during the preoperative period; the same was observed for LVEDD (r = 0.45, p = 0.002), LVM (r = 0.36, p = 0.026), LVEF (r = −0.35, p = 0.026) and aortic annulus (r = 0.43, p = 0.018) in the early postoperative period; and LVEDD (r = 0.35, p ≤ 0.05), LVM (r = 0.43, p = 0.007) and EOA (r = 0.496, p = 0.003) in the follow-up period. In the group of AS and IHD, correlations were found only with LV posterior wall thickness (r = 0.322, p = 0.022) in the follow-up period. Conclusions: Histological MF in AS was correlated with LVM and LVEDD in all study periods. No correlations between MF and LV parameters were found in aortic stenosis in the ischemic heart disease group across all study periods.

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Early Hemodynamics after Aortic Valve Replacement

Cited by 2 publications

References 27 publications

Early outcomes of patient-prosthesis mismatch following aortic valve replacement

Early outcomes of patient-prosthesis mismatch following aortic valve replacement

Histologically Validated Myocardial Fibrosis in Relation to Left Ventricular Geometry and Its Function in Aortic Stenosis

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