Early Histopathology In Oral Submucous Fibrosis (OSF) To Rule The Possibility Of Epithelial Dysplasia - Report Of Two Cases

Abstract

Oral submucous fibrosis (OSF) is a chronic scarring and progressive condition affecting the oral cavity, oropharynx and upper portion(1/3rd) of the esophagus. It is a potentially malignant disorder. It usually presents with trismus as the chronicity progresses with a palpresentation of the mucosa. Encountering a whitish patch, ulcer or a growth in the bed of Oral submucous fibrosis is something thoughtprovoking. The malignant transformation potential of Oral submucous fibrosis is comparatively higher than other premalignantconditions affecting oral cavity. The need for biopsy at any stage of OSF is a necessity to rule out underlying pathogenicity to transformtowards malignancy or dysplasia.