Early Identification of Co-Occurring Pain, Depression and Anxiety

Sherbourne, Cathy D.; Asch, Steven M.; Shugarman, Lisa R.; Goebel, Joy R.; Lanto, Andrew B.; Rubenstein, Lisa V.; Wen, Li; Zubkoff, Lisa; Lorenz, Karl

doi:10.1007/s11606-009-0956-2

Cited by 43 publications

(36 citation statements)

References 21 publications

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“…At scheduled intervals, the PI or co-PI reviewed additional abstractions for accuracy and conducted regular meetings to clarify issues that arose during the review process. Other details related to the study methods are provided elsewhere 35,36…”

Section: Methodsmentioning

confidence: 99%

Heart Failure: The Hidden Problem of Pain

Goebel

Doering

Shugarman

et al. 2009

Journal of Pain and Symptom Management

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Although dyspnea and fatigue are hallmark symptoms of heart failure (HF), the burden of pain may be underrecognized. This study assessed pain in HF and identified contributing factors. As part of a multicenter study, 96 veterans with HF (96% male, 67 ± 11 years) completed measures of symptoms, pain (Brief Pain Inventory [BPI]), functional status (Functional Morbidity Index), and psychological state (Patient Health Questionnaire-2 and Generalized Anxiety Disorder-2). Single items from the BPI interference and the quality of life-end of life measured social and spiritual well-being. Demographic and clinical variables were obtained by chart audit. Correlation and linear regression models evaluated physical, emotional, social, and spiritual factors associated with pain. Fifty-three (55.2%) HF patients reported pain, with a majority (36 [37.5%]) rating their pain as moderate to severe (pain ≥ 4/10). The presence of pain was reported more frequently than dyspnea (67 [71.3%] vs. 58 [61.7%]). Age (P = 0.02), psychological (depression: P = 0.002; anxiety: P = 0.001), social (P < 0.001), spiritual (P = 0.010), and physical (health status: P = 0.001; symptom frequency: P = 0.000; functional status: P = 0.002) well-being were correlated with pain severity. In the resulting model, 38% of the variance in pain severity was explained (P < 0.001); interference with relations (P < 0.001) and symptom number (P = 0.007) contributed to pain severity. The association of physical, psychological, social, and spiritual domains with pain suggests that multidisciplinary interventions are needed to address the complex nature of pain in HF.

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Section: Methodsmentioning

confidence: 99%

Heart Failure: The Hidden Problem of Pain

Goebel

Doering

Shugarman

et al. 2009

Journal of Pain and Symptom Management

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“…Indeed, two-thirds of pain-related outpatient visits are due to musculoskeletal pain, accounting for nearly 70 million outpatient visits in the U.S. each year [2]. In a study of 528 veteran outpatients the predominant pain complaints were musculoskeletal [8]. Two Institute of Medicine reports have summarized the enormous functional and economic impact of musculoskeletal pain on both the working and the retired population [9,10].…”

Section: Introductionmentioning

confidence: 99%

Stepped Care to Optimize Pain care Effectiveness (SCOPE) trial study design and sample characteristics

Kroenke

Krebs

et al. 2013

Contemporary Clinical Trials

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“…This insufficiently regulated inflammatory process may initiate acute pain; however, there is evidence linking PTSD to the onset of chronic pain in veterans (Helmer et al, 2009;Kline et al, 2010;Lew et al, 2009;Shipherd et al, 2007) and motor vehicle survivors (Jenewein et al, 2009). In further support of this association, additional studies report high levels of chronic pain in PTSD patients, including those seeking care as psychiatric outpatients (Villano et al, 2007), male veterans (Sherbourne et al, 2009), abused women (Taft, Schwartz, & Liebschutz, 2010;Wuest et al, 2009), and primary care patients (Frayne et al, 2004;Schur et al, 2007). Chronic pain in PTSD has also been linked to greater medical disability and a greater number of annual medical appointments (Wuest et al, 2008).…”

Section: Inflammatory-related Medical Morbidity In Ptsdmentioning

confidence: 98%