Abstract:Given the high prevalence and relapse rates of hepatocellular carcinoma (HCC), an increased capacity for early identification of patients most at risk for post-resection recurrence would help improve patient outcomes and prioritize health care resources. Here, we combined spatial multi-transcriptomics and proteomics approaches to characterize the tumor and immunological landscape of 61 samples. We observed a spatial and HCC-recurrence-associated distribution of natural killer (NK) cells in the invasive front a… Show more
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