Social science and basic and clinical research continue to demonstrate the powerful impact of sex and gender on health and disease across all organ systems and throughout the lifespan (Legato, Johnson, & Manson, 2016; Schiebinger & Stefanick, 2016). Gender and sex also influence responses to treatment, care provision, and use (Legato et al., 2016). Gender and sex should be central components of the growing precision medicine movement. However, gender and sex remain inadequately considered in clinical care, medical research, and medical education and training. Further, strategies to promote consideration of sex and gender in the activities of academic medical centers (AMCs) are not well-described. Numerous AMCs have distinct women's health centers and initiatives that lead important efforts in women's health care, research, and teaching. Given the historic underrepresentation of women in basic and clinical research studies, critical clinical and public health issues specific to women, and the value of distinct approaches to women's health, we feel that there remains value