Early Intensive Resuscitation of Patients With Upper Gastrointestinal Bleeding Decreases Mortality

Baradarian, Robin; Ramdhaney, Susan; Chapalamadugu, Rajeev; Skoczylas, Leor; Wang, Karen; Rivilis, Svetlana; Remus, Kristin; Mayer, Ira; Iswara, Kadirawel; Tenner, Scott

doi:10.1111/j.1572-0241.2004.04073.x

Cited by 181 publications

(84 citation statements)

References 11 publications

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“…As with any medical life-threatening condition, the first step in the management of a patient with UGIB should be resuscitation and it should begin at the same time as initial assessment in the emergency department (6,7). Adequate early resuscitation in patients with UGIB can minimize treatment-associated complications and decrease mortality (8).…”

Section: Resuscitation and General Managementmentioning

confidence: 99%

“…As recommended by current guidelines, when patients with UGIB present at the emergency department, clinical, laboratorial and endoscopic features should be routinely used for risk stratification (6,7,20,21).…”

Section: Risk Stratificationmentioning

confidence: 99%

“…Patients presenting with a clean base ulcer or flat spot do not need any endoscopy intervention (6,21).…”

Section: Gastroduodenal Ulcer Bleedingmentioning

confidence: 99%

“…Blood transfusion should be therefore initiated if hemoglobin is < 7 g/dL for most patients, including those with stable coronary heart disease. For those patients with unstable coronary disease, a higher threshold of < 9 g/dL should trigger transfusion support (6).…”

Section: Resuscitation and General Managementmentioning

confidence: 99%

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New insights on an old medical emergency: non-portal hypertension related upper gastrointestinal bleeding

Cúrdia-Gonçalves¹,

Rosa²,

Cotter³

2016

Rev Esp Enferm Dig

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Upper gastrointestinal bleeding (UGIB) is a potentially life-threatening condition and the most common medical emergency managed by gastroenterologists. Despite being one of the most antique medical problems, recent studies have been slowly changing the management of these patients, which should nowadays include not only initial resuscitation, but also risk stratification, pre-endoscopic therapy, endoscopy treatment, and post-procedure care. The aim of this paper is to review the extended approach to the patient with non-portal hypertension related UGIB.

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Section: Resuscitation and General Managementmentioning

confidence: 99%

Section: Risk Stratificationmentioning

confidence: 99%

“…Patients presenting with a clean base ulcer or flat spot do not need any endoscopy intervention (6,21).…”

Section: Gastroduodenal Ulcer Bleedingmentioning

confidence: 99%

Section: Resuscitation and General Managementmentioning

confidence: 99%

See 2 more Smart Citations

New insights on an old medical emergency: non-portal hypertension related upper gastrointestinal bleeding

Cúrdia-Gonçalves¹,

Rosa²,

Cotter³

2016

Rev Esp Enferm Dig

View full text Add to dashboard Cite

show abstract

“…measures will reduce mortality and morbidity in these patients. 4,5 The investigation and treatment modality of choice is upper gastrointestinal endoscopy because of its affordability and accuracy in picking up various lesions. 3,6 This study was carried out to evaluate the endoscopic findings in patients presenting with UGIB and its frequency among these patients according to gender and age.…”

Section: Introductionmentioning

confidence: 99%

Upper Gastrointestinal Bleeding; Endoscopic Findings in Patients

Ather¹,

Sarfraz

Zikarya³

2017

TPMJ

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ABSTRACT… Background: Upper gastrointestinal bleeding (UGIB) is a common medical condition requiring mostly hospitalization and resuscitation. Patients with upper GI bleeding have high morbidity. The investigation of choice in upper GI bleeding is upper GI endoscopy, because endoscopy has good, the complication rate with endoscopy are low, another advantage of using endoscopy is therapeutic interventions as well. The causes of upper GI bleeding are numerous most frequent causes being in decreasing order of frequency peptic ulcer, esophageal varices, mallory-weis tears. Other causes include tumors, erosions and arterio-venous malformations.3 Objectives: To determine the endoscopic findings in patients presenting with UGIB and frequency of various findings among these patients according to gender and age in medical ward of Allied Hospital Faisalabad. Study Design: Retrospectively reviewed and analyzed. Setting: Medical Unit 2 of Allied Hospital Faisalabad. Period: 06 month between January 2015 to June 2015. Methods: The record of 120 patients who underwent endoscopy for upper gastrointestinal bleeding. Results: Data was collected and entered on SPSS. Statistical data analysis was performed with chi-square. Statistical significance was determined at P< 0.05. Information obtained from upper gastrointestinal endoscopy were then recorded according to age, gender and presented in form of tables. Conclusions: It has been found that esophageal varices was the most commonest cause of upper gastrointestinal bleeding in the study probably due to the high prevalence of hepatitis infection and chronic liver disease in our population. Key words:Upper gastrointestinal bleeding (UGIB), Esophageal varices, Fundal varices.

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Antiplatelet and Anticoagulant Therapy in Patients With Gastrointestinal Bleeding

Almadi¹,

Barkun²,

Brophy³

2011

JAMA

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Bleeding in the upper gastrointestinal tract is a common medical problem, with an incidence of 48 to 160 cases per 1000 adults per year and a mortality rate of 5% to 14%. The risk of gastrointestinal bleeding is increased with the use of antiplatelet medications including aspirin and clopidogrel, as well as warfarin or a combination of these medications. The recurrence rate for bleeding in patients who continue to take aspirin after an episode of peptic ulcer disease-related bleeding can reach up to 300 cases per 1000 person-years and varies by age, sex, and the use of nonsteroidal anti-inflammatory medications. Using the case of Ms S, an 86-year-old woman who presented to the emergency department with an episode of nonvariceal upper gastrointestinal tract bleeding, we address the management of patients who are receiving antiplatelet or anticoagulation therapy who present with gastrointestinal bleeding, including when to restart antiplatelet or anticoagulation therapy, interventions to reduce the risk of bleeding recurrence, and the potential for drug interactions between clopidogrel and proton pump inhibitors.

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Early Intensive Resuscitation of Patients With Upper Gastrointestinal Bleeding Decreases Mortality

Abstract: Early intensive resuscitation of patients with upper gastrointestinal bleeding significantly decreases mortality. Physicians involved in the care of patients with UGIB should focus on early and rapid correction of hemodynamics, HCT, and underlying coagulopathy.

Cited by 181 publications

References 11 publications

New insights on an old medical emergency: non-portal hypertension related upper gastrointestinal bleeding

New insights on an old medical emergency: non-portal hypertension related upper gastrointestinal bleeding

Upper Gastrointestinal Bleeding; Endoscopic Findings in Patients

Antiplatelet and Anticoagulant Therapy in Patients With Gastrointestinal Bleeding

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