The present paper discussed the treatment of a 13-year-old female having a Class III molar and canine relationships (C3M) in the right side and complicated by anterior and unilateral posterior crossbite in the left side. After discussing treatment plans with the patient, a unilateral extraction of tooth #44 to shift her midline and treat her right C3M canine relationship was scheduled. Crossbite elastics were used for her left from palatal side of maxillary posterior teeth to buccalside of mandibular posterior teeth. 2 years post follow up, correction of both the anterior and posterior crossbites were achieved, leading to enhanced functional occlusion and improved overjet and overbite measurements.