Early interventions with parental participation and their implications on the neurodevelopment of premature children: a systematic review and meta-analysis

Bernabe-Zuñiga, Jose Enrique; Rodriguez-Lucenilla, Maria Isabel; Alias-Castillo, Antonio Javier; Rueda-Ruzafa, Lola; Roman, Pablo; del Mar Sanchez-Joya, Maria

doi:10.1007/s00787-024-02528-1

Eur Child Adolesc Psychiatry

2024

DOI: 10.1007/s00787-024-02528-1

|View full text |Cite

Early interventions with parental participation and their implications on the neurodevelopment of premature children: a systematic review and meta-analysis

Jose Enrique Bernabe-Zuñiga,

Maria Isabel Rodriguez-Lucenilla,

Antonio Javier Alias-Castillo

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Neurobehavioral disorders among children born to mothers exposed to illicit substances during pregnancy

Chen,

Lee,

et al. 2024

BMC Med

View full text Add to dashboard Cite

Background Exposure to illicit substances during pregnancy may have long-term impacts on children’s neurodevelopment. This study explores subsequent risks for intellectual disability, autistic disorders, and attention deficit and hyperactivity disorders in children born to mothers exposed to illicit substances before or during pregnancy. Methods We identified women with illicit drug use by linking the police records from the “Substance Abuse Control Databases” and Taiwan Birth Registration and Birth Notification records from 2004 to 2014. Children whose mothers that had exposed to illicit substances during pregnancy identified from the police records were the “substance-exposed cohort.” A 1:1 ratio exact-matched comparison cohort based on child’s gender, child’s birth year, mother’s birth year, and child’s first use of the health insurance card, as well as a “propensity score (PS)-matched” comparison cohort of children born by substance-unexposed mothers, was established. Multivariate Cox regression analyses with competing risk models were performed. Results Higher incidences of intellectual disability (adjusted hazard ratio (aHR) = 2.41, 95% confidence interval (CI): 1.15–5.03) and attention deficit and hyperactivity disorder (ADHD) (aHR = 2.35, 95% CI: 1.63–3.28) were found in children prenatally exposed to illicit substances during pregnancy compared to exact-matched non-exposed cohorts. Adjusted risks of ADHD were significantly higher in mothers exposed to substances during pregnancy (aHR = 1.77 (1.42–2.21)) and before pregnancy (aHR = 1.43 (1.14–1.80)) compared to PS-matched unexposed cohorts after adjusting for covariates. Conclusions This is one of the first studies using large population-based data linked to criminal records to reveal increased risks of intellectual disability and ADHD in children with prenatal exposure to illicit substances compared to matched unexposed controls. Our results also highlight the importance of preventive measures and interventions for the well-being of both the mother and the child. Supplementary Information The online version contains supplementary material available at 10.1186/s12916-024-03762-9.

show abstract

Neurobehavioral disorders among children born to mothers exposed to illicit substances during pregnancy

Chen,

Lee,

et al. 2024

BMC Med

View full text Add to dashboard Cite

show abstract

Aggressive and Autoaggressive Behaviors in Patients with Autism Spectrum Disorder in Correlation with Middle Cerebral Artery Flow Velocity

Abakumow,

Przybylski,

Słoma

et al. 2024

JPM

View full text Add to dashboard Cite

Background/Objectives The purpose of this study was to see whether there is a correlation between the behavior of autism spectrum disorder patients and brain abnormalities based on the velocity of blood flow in the MCA (middle cerebral artery). Methods: The use of HAP (High Altitude Protection) suits, which are used in aviation, to treat patients with ASD (autism spectrum disorder) causes significant changes in their functioning and physiological processes. These changes are not only noted in psychological tests but are observed in cerebral blood flow using transcranial Doppler ultrasound of the MCA. Results The results of this study made it possible to distinguish two groups with different flow velocities, which can be characterized as flows of less than 80 cm/s and flows of more than 80 cm/s. In addition, it was shown that in patients with elevated blood flow velocity, aggressive behaviors account for 86.96%, while self-aggressive behaviors account for 65.2%. On the other hand, in the case of patients with reduced flow velocity, i.e., less than 80 cm/s, the rate of aggressive behavior is 20% and that of self-aggressive behavior is 50%. The experiment showed that after therapy, there is a normalization of blood flow, which increased in the case of patients with a reduced flow rate below 80 cm/s and, in the case of elevated blood velocity after therapy, decreased towards normal levels. Conclusions The observed rate of normalization of flow velocities in the MCA translated into significant changes in the behavior and functioning of patients in the neurotypical direction, which was noticeable in the psychological tests conducted.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Early interventions with parental participation and their implications on the neurodevelopment of premature children: a systematic review and meta-analysis

Cited by 2 publications

References 55 publications

Neurobehavioral disorders among children born to mothers exposed to illicit substances during pregnancy

Neurobehavioral disorders among children born to mothers exposed to illicit substances during pregnancy

Aggressive and Autoaggressive Behaviors in Patients with Autism Spectrum Disorder in Correlation with Middle Cerebral Artery Flow Velocity

Contact Info

Product

Resources

About