Early Life Displacement Due to Armed Conflict and Violence, Early Nutrition, and Older Adult Hypertension, Diabetes, and Obesity in the Middle-Income Country of Colombia

McEniry, Mary; Samper‐Ternent, Rafael; Flórez, Carmen Elisa; Cano-Gutiérrez, Carlos

doi:10.1177/0898264318778111

Cited by 9 publications

(10 citation statements)

References 40 publications

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“…Individuals with disadvantaged childhood SES have an increased likelihood of experiencing childhood food shortage 28 , which is linked to a range of late-life health outcomes 25 . Exposure to childhood food shortage, particularly prolonged hunger, is related to a 14.6% increase in the probability of being overweight and a 5.3% increase in the likelihood of being obese 29 , which is correlated with a higher risk for metabolic disorders, including T2D 29 .…”

Section: Introductionmentioning

confidence: 99%

Life-course pathways from childhood socioeconomic status to type 2 diabetes in mid-late Chinese adulthood

Zhang

Jiang

Sha³

et al. 2021

Sci Rep

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The relationship between childhood socioeconomic status (SES) and type 2 diabetes (T2D) remains inconclusive, and the pathways and mechanisms driving this relationship have yet to be clarified. This study aimed to examine the pathways linking childhood SES to T2D prevalence in mid-late adulthood in a low- and middle-income country. The incidence of T2D diagnosed in mid-late Chinese adulthood was assessed using self-reports from the Health and Retirement Longitudinal Study (CHARLS). Childhood SES was assessed by the education, occupation, survivorship of the parents and the financial situation of the family, whereas adulthood SES was assessed by education and wage. This study performed structural equation modeling to clarify the direct and indirect pathways from childhood SES to T2D via childhood health, childhood food shortage, adulthood SES and physical activity. A total of 15,132 participants were included, and the prevalence of T2D was 5.24%. This study found that childhood SES was directly associated with T2D in mid-late adulthood, the probability of developing T2D increased by 9.20% of the standard deviation for each decrease in standard deviation in childhood SES. Childhood SES was indirectly associated with T2D via adulthood SES, physical activity, childhood health and food shortage. Adulthood SES and physical activity mainly mediated the indirect pathway from childhood SES and T2D. This study showed direct and indirect pathways from disadvantaged childhood SES to increased risk of T2D in mid-late Chinese adulthood. Childhood SES, adulthood SES, physical activity, childhood health and food shortage were identified as life-course interventional targets that should be considered in the development of effective strategies to reduce the burden of T2D and SES-related health inequities in childhood.

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Section: Introductionmentioning

confidence: 99%

Life-course pathways from childhood socioeconomic status to type 2 diabetes in mid-late Chinese adulthood

Zhang

Jiang

Sha³

et al. 2021

Sci Rep

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“…The SABE-Columbia survey, comprised of 23,694 Columbian respondents, 60 years and older, illustrates that displacement throughout one's childhood correlates with at least one chronic illness in approximately 68% of respondents [9]. A 2018 study surveying approximately 8000 children that encountered armed conflict or displacement exposed significant prevalence of PTSD (47%), depression (43%) and anxiety (27%) [10]. Several studies illustrate a predisposition and an increased risk of ill-health into adulthood as a result of an inappropriate activation of biological and behavioral mechanisms commonly identified in conditions like PTSD and the aforementioned mood disorders.…”

Section: Relationship Among Aces and Chronic Diseasementioning

confidence: 99%

The Relationship of Adulthood Chronic Disease and Adverse Childhood Experiences (ACEs): Implications Regarding Prevention and Promotion in International Health

Holter¹,

Marchionni²,

Bhatt³

2021

Contemporary Developments and Perspectives in International Health Security - Volume 1

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Several studies, including the innovative 1998 ACE Study by CDC-Kaiser Permanente, have assessed the association among adulthood chronic disease and the prevalence of maladaptive, health-harming behaviors including: excessive alcohol use, tobacco use, physical inactivity, psychiatric illness including suicidal ideation or attempts, promiscuous sexual behavior (>50 sex partners), history of STI/STD and severe obesity (obesity (BMI > 35 kg/m 2)), subsequent to an individual's exposure to adverse childhood experiences (ACEs). Individuals that have encountered numerous instances of ACEs are almost twice as likely to die before the age of 75, demonstrating a dose-dependent relationship between the instances of ACEs and an increased morbidity/mortality in regard to chronic disease. This excerpt examines the contribution of ACEs to chronic disease and the consequential maladaptive behavior to said adversity, the consequential physiologic and biomolecular changes explained by the Biological Embedding of Childhood Adversity Model in addition to the implications of recounted ACEs on international health security in regard to concepts like conflict, displacement and food insecurity. The apparent association among adulthood chronic disease and ACEs demand changes that promote preventative processes as a means to address the implications these interconnections have on international health.

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“…Ріст захворюваності на ЦД в осіб, які пройшли війну, є відомим фактом [9][10][11]14 the frequency of complications of diabetes and concomitant pathology in patients with type 1 and type 2 diabetes from the territory of military conflict. n. Significant differences in the studied indicators depending on the sex of patients (in the absence of significant differences in indicators for other categories of patients): in patients with type 1 diabetes mellitus, a higher frequency of MI, SDS, aCSg, hypertension and cancer, the frequency of short-acting gII and shortacting insulin analogues; patients with type 1 diabetes mellitus have a higher frequency of DDnP, DEP, CVD and other endocrine diseases, the frequency of administration of 2 insulin drugs, insulin analogues in general and long-acting insulin analogues; patients with type 2 diabetes have a higher frequency of SDS, frequency of administration of short-acting insulin analogues, drugs from the group of gliclazide and Clinical Endocrinology and Endocrine Surgery / Клінічна ендокринологія та ендокринна хірургія 3 (71) 2020 О OrIgInal rESEarCh / ОРИГІНАЛЬНІ ДОСЛІДЖЕННЯ DDP-4 inhibitors; in patients with type 2 diabetes mellitus more frequency of cancer and other endocrine diseases, the frequency of insulin therapy.…”

Section: результати та обговоренняmentioning

confidence: 99%

The impact of the military conflict in Eastern Ukraine on the course, tactics and effectiveness of treatment of diabetes mellitus

Krushynska¹,

Yuzvenko²,

Pankiv³

2020

CE&ES

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Early Life Displacement Due to Armed Conflict and Violence, Early Nutrition, and Older Adult Hypertension, Diabetes, and Obesity in the Middle-Income Country of Colombia

Abstract: Colombian data provide new evidence into how early life conditions and adult obesity contribute to older adult health.

Cited by 9 publications

References 40 publications

Life-course pathways from childhood socioeconomic status to type 2 diabetes in mid-late Chinese adulthood

Life-course pathways from childhood socioeconomic status to type 2 diabetes in mid-late Chinese adulthood

The Relationship of Adulthood Chronic Disease and Adverse Childhood Experiences (ACEs): Implications Regarding Prevention and Promotion in International Health

The impact of the military conflict in Eastern Ukraine on the course, tactics and effectiveness of treatment of diabetes mellitus

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