2019
DOI: 10.1101/690701
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Early life maturation of human visual system white matter is altered by monocular enucleation

Abstract: Monocular enucleation early in life and the resultant lack of binocular visual input during visual development results in functional and structural brain changes in adulthood, including alterations in white matter microstructure. However, the time courses of these neurodevelopmental changes are unknown. Here, we investigated whether structural brain changes were present at 8 to 12 years of age in a group of children with a history of monocular enucleation prior to 3 years of age (the ME group) relative to cont… Show more

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