Early mechanical cardiopulmonary resuscitation can improve outcomes in patients with non-traumatic cardiac arrest in the emergency department

Abstract

Objective To compare the outcomes of patients with non-traumatic cardiac arrest (CA) who received early versus late mechanical cardiopulmonary resuscitation (CPR) with the Lund University Cardiac Assist System (LUCAS) device in the emergency department (ED). Methods This was a retrospective observational study in the ED of a single medical center performed from May 2018 to December 2019; 68 patients with CA were eligible. We grouped the patients according to the time to initiating LUCAS use after CA into an early group (≤4 minutes) and late group (>4 minutes). Results The rate of return of spontaneous circulation (ROSC) was higher in the early group vs the late group (69.2% vs 52.4%, respectively). The 4-hour survival rate was significantly higher in the early group vs the late group (83.3% vs 45.5%, respectively), and CPR duration was significantly shorter in the early group (23.3 ± 12.5 vs 31.1 ± 14.8 minutes, respectively). Conclusion Early mechanical CPR can improve the success of achieving ROSC and the 4-hour survival rate in patients with non-traumatic CA in the ED, considering that more benefits were observed in patients who received early vs late LUCAS device therapy.

Lund University Cardiac Arrest System and Percutaneous Coronary Intervention During Cardiac Arrest: Case Report and Review of Literature

“…A key factor in reaching optimal survival rates in cardiac arrest patients revolves around the timing of LUCAS application. In a single-center retrospective observational study of IHCA (containing 68 patients) in the emergency department, early LUCAS application led to higher four-hour survival rates compared to LUCAS application with a delay of four minutes or more (p<0.05) [ 6 ]. While statistical significance was not met owing to the small sample size, numerically more patients in the early LUCAS group achieved ROSC and survived admission [ 6 ].…”