2008
DOI: 10.1016/j.parkreldis.2008.01.007
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Early neuropsychological detection and the characteristics of Parkinson's disease associated with mild dementia

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Cited by 25 publications
(34 citation statements)
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“…Patterns of responding (impaired organizational strategies and positive response bias) again suggest that these deficits are primarily related to frontal-executive dysfunction rather than memory loss mediated by the temporal lobes [47, 49, 52]. However, PD has also been associated with temporal and parietal hypoperfusion and atrophy [5359], and some PDD patients also have neuropathologic changes consistent with AD [31, 60, 61]. As a result, some individuals with PD may present with AD-like memory impairments that are independent of executive dysfunction [48].…”
Section: Level Imentioning
confidence: 99%
See 1 more Smart Citation
“…Patterns of responding (impaired organizational strategies and positive response bias) again suggest that these deficits are primarily related to frontal-executive dysfunction rather than memory loss mediated by the temporal lobes [47, 49, 52]. However, PD has also been associated with temporal and parietal hypoperfusion and atrophy [5359], and some PDD patients also have neuropathologic changes consistent with AD [31, 60, 61]. As a result, some individuals with PD may present with AD-like memory impairments that are independent of executive dysfunction [48].…”
Section: Level Imentioning
confidence: 99%
“…Visuospatial dysfunction, which may be among the first cognitive changes noticed in PD [59, 77], is predictive of both cognitive decline and eventual dementia [78, 79]. The neuroanatomic substrate of defective visuospatial processing in PD is not well understood, but is hypothesized to result from asymmetric dopamine loss in the right basal ganglia [80], deficits in the dorsolateral prefrontal pathways with resulting structural and functional changes in the parietal lobes [81, 82], disruptions in the fronto-striatal loop [83], or other neuropathologic changes in the temporal, parietal, and/or occipital lobes [84].…”
Section: Level Imentioning
confidence: 99%
“…26 Cognitive issues, including attention, executive function, visual-spatial impairments and memory, and dementia, are more frequent in patients with PD than in age-matched controls. 16,17 Cognitive impairments correlate with gait and postural function. 18 Depressive symptoms may be found in as many as 40% of PD patients and may also impact motor functioning.…”
Section: Discharge Needs In Parkinson Diseasementioning
confidence: 99%
“…In PD, MCI may present with executive dysfunction [7] and visual-spatial deficits [8]. MCI exists as a prodromal stage for PDD.…”
Section: Introductionmentioning
confidence: 99%