Early-onset hidradenitis suppurativa

Palmer, Richard A.; Keefe, M.

doi:10.1046/j.1365-2230.2001.00876.x

Cited by 83 publications

(80 citation statements)

References 13 publications

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“…HS seems to develop rarely before puberty or after the menopause, although the persistence of existing lesions after the menopause is not unusual. It was reported that only 2% of cases occur before the age of 11 years [13]. However, evidence from a cross-sectional study indicates that 7.7% of HS patients reported prepubertal early onset [14].…”

Section: Epidemiologymentioning

confidence: 99%

Hidradenitis Suppurativa/Acne Inversa: Criteria for Diagnosis, Severity Assessment, Classification and Disease Evaluation

Zouboulis¹,

Marmol²,

Mrowietz³

et al. 2015

Dermatology

304

265

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Background: Hidradenitis suppurativa/acne inversa (HS) is a chronic, inflammatory, recurrent, debilitating disease, which inflicts a significant burden on patients and is associated with comorbid disorders, such as significantly reduced quality of life, depression, stigmatization, inactivity, working disability, impairment of sexual health and several cardiovascular risk factors. Aims/Methods: To implement an expert consensus on the diagnostic criteria, severity and classification assessment, and an assessment of anti-inflammatory treatment effectiveness based on current evidence. Results: This article provides criteria for diagnosis, severity assessment, classification and evaluation of HS patients. Conclusion: The provided criteria can be used as tools for the promotion of uniformity in HS evaluation and facilitation of early and timely identification and referral in the primary care setting and thorough and efficient evaluation in daily clinical practice.

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Section: Epidemiologymentioning

confidence: 99%

Hidradenitis Suppurativa/Acne Inversa: Criteria for Diagnosis, Severity Assessment, Classification and Disease Evaluation

Zouboulis¹,

Marmol²,

Mrowietz³

et al. 2015

Dermatology

304

265

View full text Add to dashboard Cite

show abstract

“…Estimated incidence and prevalence of HS during adolescence ranges from 1.5 to 2.6 cases/100,000 population and from 0.016 to 0.2%, respectively [5-8]. Among HS patients, the proportion with an adolescent onset changes depending on the used age limits from 2% under 11 years old to 38.3% under 17 years old [9-12]. …”

Section: Introductionmentioning

confidence: 99%

Adolescent-Onset Hidradenitis Suppurativa: Prevalence, Risk Factors and Disease Features

Molina-Leyva

Cuenca‐Barrales

2018

Dermatology

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Background/Aims: Hidradenitis suppurativa (HS) is a chronic inflammatory and destructive skin disorder. Early diagnosis and treatment are critical to stop its progression. Data concerning adolescent-onset HS are scarce. The aims of this study are to describe the prevalence of adolescent-onset HS and to explore potential risk factors and the disease features of these patients. Patients and Methods: A cross-sectional study including 134 patients was performed. Results: Adolescent-onset HS occurred in 51.5% (69/134) of patients. Adolescent-onset HS was associated with female sex, positive family history, presence of pilonidal sinus, acne conglobata, longer disease duration and a worse perception of disease severity. Conclusion: Adolescent-onset HS might be more frequent than previously reported. Female sex, positive family history and the presence of elements of the follicular occlusion tetrad identify individuals with a higher risk of early onset. These patients experience a longer disease duration and perceive their disease as severer.

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“…Typically, disease onset occurs in the second or third decade of life. 2 Although HS may be seen in prepubertal patients, [2][3][4][5] fewer than 2% of cases occur before the age of 11 years. 2 Patients with HS often report a significant negative effect on quality of life, due not only to physical symptoms but also to social stigma associated with the disease.…”

mentioning

confidence: 99%

“…2 Although HS may be seen in prepubertal patients, [2][3][4][5] fewer than 2% of cases occur before the age of 11 years. 2 Patients with HS often report a significant negative effect on quality of life, due not only to physical symptoms but also to social stigma associated with the disease. 6 Although multiple medical treatments exist, including antimicrobials, immunosuppressants, and hormonal, laser, and surgical therapies, no single treatment modality has been found to be universally effective.…”

mentioning

confidence: 99%

Finasteride for the Treatment of Hidradenitis Suppurativa in Children and Adolescents

Randhawa

Hamilton²,

Pope³

2013

JAMA Dermatol

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Importance: Hidradenitis suppurativa (HS) is a chronic debilitating cutaneous disease for which there is no universally effective treatment. Patients typically present at puberty with tender subcutaneous nodules that can progress to dermal abscess formation. Antiandrogens have been used in the treatment of HS, and studies have primarily focused on adult patients.Observations: We present a case series of 3 pediatric patients with HS who were successfully treated with oral finasteride, resulting in decreased frequency and severity of disease flares with no significant adverse effects. Conclusions and Relevance:Finasteride is a therapeutic option that provides benefit for pediatric patients with HS. Further prospective data and randomized controlled studies will provide helpful information in the management of this disease.

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Early-onset hidradenitis suppurativa

Cited by 83 publications

References 13 publications

Hidradenitis Suppurativa/Acne Inversa: Criteria for Diagnosis, Severity Assessment, Classification and Disease Evaluation

Hidradenitis Suppurativa/Acne Inversa: Criteria for Diagnosis, Severity Assessment, Classification and Disease Evaluation

Adolescent-Onset Hidradenitis Suppurativa: Prevalence, Risk Factors and Disease Features

Finasteride for the Treatment of Hidradenitis Suppurativa in Children and Adolescents

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