Early-Onset Severe Preeclampsia in Nigerian Women: Determining a Balance between Maternal Wellbeing and Fetal Survival in a Resource-Limited Setting

Enaruna, Nosakhare; Sodje, Jedidiah Dase Kingsley

doi:10.9734/bjmmr/2015/19217

Cited by 4 publications

(3 citation statements)

References 24 publications

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“…Enaruna et al observed that Severe anemia was 7.7-fold more associated with maternal mortality in severe preeclampsia cases than no anemia. 4 Abruption was seen in 8.88% cases than 0.5% controls, ARF was seen in 2.2% cases than in 0.5% control. Pulmonary edema seen in 5% cases, PPH occurred in 2.8% cases, CCF in 3.3%, HELLP in 1.6%, CVA 1.1%, Pulmonary embolism and DIC in 0.5% cases.…”

Section: Thus Incidence Of Preeclampsia In Sultania Zananamentioning

confidence: 84%

“…1 Enaruna et al found 30 years (range: 19 to 41) and Assis et al found that age above 30 years was associated with a risk for preeclampsia. 4,5 Andhra Pradesh found the highest prevalence of anaemia (68.4%) in the age group 20-24 years . There has been increased risk of anaemia among pregnant adolescents (teenage pregnancy) due to depleted iron stores that occurred during the adolescent growth spurt.…”

Section: Thus Incidence Of Preeclampsia In Sultania Zananamentioning

confidence: 99%

“…12 Enaruna et al observed stillbirth (32.8% more) and ENND (13.8% more) were significantly associated with severe anemia in severe preeclampsia cases. 4 Liu et al observed the proportion of babies who stayed alive up to 7 days after delivery was significantly reduced by the presence of severe anemia. 13 The increased incidence of perinatal morbidity and mortality seen in pregnancies complicated by preeclampsia, is due to the need for premature delivery and utero-placental insufficiency resulting in compromised blood supply to the fetus but presence of severe anemia contribute to adverse outcome of severe preeclampsia .…”

Section: Thus Incidence Of Preeclampsia In Sultania Zananamentioning

confidence: 99%

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A case control study to evaluate correlation of anemia with severe preeclampsia

Gupta

2018

Int J Reprod Contracept Obstet Gynecol

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INTRODUCTIONHypertensive disorders of pregnancy and their complications rank as one of the major cause of maternal mortality and morbidity in the world. Amongst them, preeclampsia is emerging as one of the most common complication of pregnancy.Pre-eclampsia is a multi-system disorder of unknown aetiology, unique to pregnancy, with onset after 20 weeks of gestation.Although, the exact aetiology of preeclampsia is not yet known, many factors such as low education, prim parity, family history of hypertension, obesity, younger and advanced maternal age and malnourishment are proven as its risk factors and evidence suggests that various other factors like severe anemia could also be a risk factor for development of preeclampsia and that cannot be ignored.The uncertainty of cause of a disease of such common occurrence worldwide, make it to be more studied. Several studies have shown the association between severe anemia and preeclampsia and thus considers anemia as one of the main and treatable risk factor for preeclampsia.Anemia during pregnancy is a major public health problem especially in developing countries which itself increases the maternal mortality, in addition it further ABSTRACT Background: Preeclampsia is a leading cause of maternal and perinatal morbidity and mortality worldwide. This study aims to evaluate correlation of anemia with severe preeclampsia. Methods: It is a prospective case control study conducted in Sultania Zanana Hospital, Bhopal over one year period. Patients were grouped as cases (severe preeclampsia with severe anemia, n=180) and controls (severe preeclampsia with no/mild/moderate anemia, n=180). Collecting data were compared using the Pearson chi square, fisher's exact test and the independent t-test as appropriate. Logistic regression analysis was performed. Odds ratio (OR) and their corresponding 95% confidence intervals were calculated. Results: Higher incidence of maternal complications abruption (8.88% v/s 0.5%), ARF (2.2% v/s 0.5%), PPH (2.8%), pulmonary edema (5%), CCF (3.3%), HELLP (1.6%), CVA (1.1%), pulmonary embolism and DIC in 0.5% and maternal mortality seen in cases. Perinatal complications like pregnancy wastage (22.8% v/s 7.8%), IUGR (55.8% v/s 32%), early neonatal death (7.5% v/s 2.4%), NICU admission (31.3% v/s 20.7%) were more in cases. Conclusions: Perinatal and maternal complications are significantly associated with severity of anemia in preeclampsia women. Anemia being a easily detectable and modifiable risk factor, detection of anemia in early gestation can be a key to prevent or decrease the severity of preeclampsia.

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Section: Thus Incidence Of Preeclampsia In Sultania Zananamentioning

confidence: 84%

Section: Thus Incidence Of Preeclampsia In Sultania Zananamentioning

confidence: 99%

Section: Thus Incidence Of Preeclampsia In Sultania Zananamentioning

confidence: 99%

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A case control study to evaluate correlation of anemia with severe preeclampsia

Gupta

2018

Int J Reprod Contracept Obstet Gynecol

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Fetal Growth Abnormalities: Intrauterine Growth Restriction and Macrosomia

Sodje

2021

Contemporary Obstetrics and Gynecology for Developing Countries

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Incidence and natural history of preeclampsia/eclampsia at the university maternity of Antananarivo, Madagascar: high prevalence of the early-onset condition

Ratsiatosika

Razafimanantsoa

Andriantoky

et al. 2018

The Journal of Maternal-Fetal & Neonatal Medicine

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We have in Madagascar a high rate of early-onset preeclampsia/eclampsia EOP (37% versus approximately 10% in international literature) and a consequent worrying rate of maternal-fetal mortality. We could find other high incidence of EOP in nine other geographical locations: Guadeloupe (31%), Réunion (31%), Mauritius (34%), Cameroon (37.4%), China (38%), Zimbabwe (58%), Thailand (34%), Turkey (29%), and India (26%). Emerging and tropical countries may belong to the "high rate of EOP standard." There is an urgent need to have additional data from these areas to confirm the hypothesis.

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Early-Onset Severe Preeclampsia in Nigerian Women: Determining a Balance between Maternal Wellbeing and Fetal Survival in a Resource-Limited Setting

Cited by 4 publications

References 24 publications

A case control study to evaluate correlation of anemia with severe preeclampsia

A case control study to evaluate correlation of anemia with severe preeclampsia

Fetal Growth Abnormalities: Intrauterine Growth Restriction and Macrosomia

Incidence and natural history of preeclampsia/eclampsia at the university maternity of Antananarivo, Madagascar: high prevalence of the early-onset condition

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