Early postnatal changes in the perfusion index in term newborns with subclinical chorioamnionitis

Felice, Claudio De; Vecchio, Antonio Del; Criscuolo, Mario; Lozupone, A.; Parrini, Stefano; Latini, Giuseppe

doi:10.1136/adc.2004.068882

Cited by 49 publications

(49 citation statements)

References 22 publications

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“…HCA is a wellknown risk for neonatal sepsis but is not obviously equivalent. For instance, this difference in terms of thymus histology concerning the HCA-associated acute thymic involution has been explored (21).…”

Section: Discussionmentioning

confidence: 99%

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Early dynamic changes in pulse oximetry signals in preterm newborns with histologic chorioamnionitis

Felice

Goldstein²,

Parrini³

et al. 2006

Pediatric Critical Care Medicine

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Section: Discussionmentioning

confidence: 99%

“…These current limitations have stimulated a search for new, real-time indices of neonatal severity based on different concepts. We have previously assessed the potential value of skin colorimetry (33,34), skin spectrophotometry (35), and pulse oximetry-derived PI (19,21) in identifying different categories of higher-severity newborns.…”

Section: Discussionmentioning

confidence: 99%

Early dynamic changes in pulse oximetry signals in preterm newborns with histologic chorioamnionitis

Felice

Goldstein²,

Parrini³

et al. 2006

Pediatric Critical Care Medicine

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“…In particular, a PI value of ^ 1.24 has been shown to be an accurate predictor for assessing the severity of neonatal illness [5] . In addition, early PI monitoring has been shown to be helpful in iden-tifying preterm and term neonates born to mothers with chorioamnionitis, a major predictor of morbidity and mortality in very low birth weight infants [8][9][10] . Moreover, PI values might be a useful additional tool for early detection of duct-dependent systemic circulation (left heart obstructive disease) [11] .…”

Section: Introductionmentioning

confidence: 99%

First Day of Life Reference Values for Pleth Variability Index in Spontaneously Breathing Term Newborns

2011

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Background: The perfusion index (PI), derived from the pulse oximetry signal, has been shown to be an accurate predictor for identifying high illness severity in neonates. The plethysmographic variability index (PVI) is a measure of the dynamic change in PI occurring during a complete respiratory cycle. Objectives: The aim of this study was to establish the reference range of PVI in spontaneously breathing term newborns. Methods: PI and PVI values were assessed in 242 term newborns during the first day of life. Results: The median PVI value on the first day of life was 20% [95% confidence interval (CI) for the mean 19–20%; inter-quartile range 15 (95% CI 15–16) – 24 (95% CI 23–24)]. The 10th and 90th percentile cutoff values were 12% (95% CI 11–12) and 28% (95% CI 27–29), respectively, with the 97.5th percentile of 35% (95% CI 34–38). PVI was also significantly influenced by the behavioral status of the newborn, and was positively correlated with PI and pulse rate, while it was inversely correlated with oxygen saturation (p < 0.0001). Conclusions: Our findings suggest: (1) evaluation of PVI values is an easily applicable, noninvasive procedure for monitoring early postnatal respiratory changes in newborns, and (2) the feasibility of a noninvasive pulse-oximeter postnatal screening for early identification of adverse neonatal cardiorespiratory outcomes.

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“…PI immediately after birth predicted the development of chorioamnionitis, a condition associated with signifi cant morbidity and mortality. PI had a 93.7 % positive predictive value and 100 % negative predictive value in identifying subclinical chorioamnionitis; early detection of chorioamnionitis enabled early treatment which decreased disease severity and admission to a neonatal critical care unit [ 30 ]. Similarly, PI has been evaluated to predict the severity of illness for other conditions in neonates [ 31 ].…”

Section: The Cardiovascular Systemmentioning

confidence: 98%

Monitoring the Neonate: Basic Science

Patiño

Kurth

McAuliffe

2014

Neonatal Anesthesia

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Pulse Oximetry: The use of pulse oximetry to measure arterial oxygen saturation in anesthesiology is standard of care. Pulse oximetry relies on the Beer-Lambert law, which relates the concentration of a chromophore to light absorption, optical path length, and extinction coeffi cient. In pulse oximetry, the chromophores of interest are oxy and deoxyhemoglobin. Because there are two chromophores, two wavelengths in which the extinction coeffi cient of oxy and deoxyhemoglobin differ are required to determine

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Early postnatal changes in the perfusion index in term newborns with subclinical chorioamnionitis

Cited by 49 publications

References 22 publications

Early dynamic changes in pulse oximetry signals in preterm newborns with histologic chorioamnionitis

Early dynamic changes in pulse oximetry signals in preterm newborns with histologic chorioamnionitis

First Day of Life Reference Values for Pleth Variability Index in Spontaneously Breathing Term Newborns

Monitoring the Neonate: Basic Science

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