Early postnatal exposure to a cafeteria diet interferes with recency and spatial memory, but not open field habituation in adolescent rats

Wait, Janina; Burns, Catherine A.; Jones, Taylor; Harper, Zoe; Allen, E. D.; Langley‐Evans, Simon C.; Voigt, Jörg-Peter

doi:10.1002/dev.22063

Cited by 5 publications

(4 citation statements)

References 91 publications

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“…Habituation refers to a decrement in responding to a relatively weak stimulus because of simple re‐exposure to that stimulus, being a primitive form of non‐associative learning (Parsons et al, 1973; Rankin et al, 2009). Therefore, comparison of exploratory activity (vertical or horizontal) between two sessions might be taken as an index of habituation to a new environment, as reported by Wait et al (2021). In addition, reaction to novelty (RN) can be evaluated through the measurement of the EA in the first session of the OF because it is motivated by novel stimuli triggered by the new environment to which the animal is exposed, as suggested by Ennaceur et al (2009) and Giuliani et al (1994).…”

Section: Methodsmentioning

confidence: 99%

Behavioural alterations induced by intermittent ethanol intake and noise exposure in adolescent rats

Buján

D’Alessio

Serra

et al. 2022

Eur J of Neuroscience

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Alcohol intake and exposure to noise are common activities of human adolescents performed in entertainment contexts worldwide that can induce behavioural disturbances. Therefore, the aim of the present work was to investigate in an experimental model of adolescent animals whether noise exposure and intermittent ethanol intake, when present individually or sequentially, might be able to modify different behaviours. Adolescent Wistar rats of both sexes were subjected to voluntary intermittent ethanol intake for 1 week followed by exposure to noise for 2 h and tested in a battery of behavioural tasks. Data show that males exposed to noise experienced a deficit in associative memory (AM), increase in anxiety-like behaviours (ALB) and altered reaction to novelty (RN) when compared with sham animals, whereas females also showed an increase in risk assessment behaviours (RABs) and a decrease in exploratory activity (EA). In contrast, ethanol intake induced an increase in RAB and RN in males and females, whereas females also showed a deficit in AM and EA as well as an increase in ALB. When ethanol was ingested before noise exposure, most parameters were counteracted both in male and females, but differed among sexes. In consequence, it could be hypothesized that an environmental acute stressor like noise might trigger a behavioural counteracting induced by a previous repeated exposure to a chemical agent such as ethanol, leading to a compensation of a non-adaptive behaviour and reaching a better adjustment to the environment.

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Section: Methodsmentioning

confidence: 99%

Behavioural alterations induced by intermittent ethanol intake and noise exposure in adolescent rats

Buján

D’Alessio

Serra

et al. 2022

Eur J of Neuroscience

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“…Contrary to the positive effects of probiotics and plant-based prebiotics on the gutbrain axis, the effects of diets which resemble a westernised diet such as high-fat diets or cafeteria diets on the pathways discussed remain to be elucidated. Current literature shows such westernised diets impair memory, alter neuroplasticity in key brain regions involved in depression, and increase neuroinflammation [141][142][143]. However, whether these effects modulate stress-related brain-to-gut and gut-to-brain mechanisms is unclear since studies evaluating brain and behaviour in conjunction with gut health in well-established animal models of stress and depression are lacking.…”

Section: Diet Stress and Intestinal Barrier Integritymentioning

confidence: 99%

The Effects of Stress and Diet on the “Brain–Gut” and “Gut–Brain” Pathways in Animal Models of Stress and Depression

Herselman

Bailey

Bobrovskaya

2022

IJMS

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Compelling evidence is building for the involvement of the complex, bidirectional communication axis between the gastrointestinal tract and the brain in neuropsychiatric disorders such as depression. With depression projected to be the number one health concern by 2030 and its pathophysiology yet to be fully elucidated, a comprehensive understanding of the interactions between environmental factors, such as stress and diet, with the neurobiology of depression is needed. In this review, the latest research on the effects of stress on the bidirectional connections between the brain and the gut across the most widely used animal models of stress and depression is summarised, followed by comparisons of the diversity and composition of the gut microbiota across animal models of stress and depression with possible implications for the gut–brain axis and the impact of dietary changes on these. The composition of the gut microbiota was consistently altered across the animal models investigated, although differences between each of the studies and models existed. Chronic stressors appeared to have negative effects on both brain and gut health, while supplementation with prebiotics and/or probiotics show promise in alleviating depression pathophysiology.

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“…This suggests Western diet decreases the quality of "what" memories in episodic memory. In fact, even exposing lactating mothers to a Western diet impaired elements of episodic memory (object location and recency learning) in their weaning pups when tested in adolescence (Wait et al, 2021).…”

Section: Evidence From Non-human Animal Studiesmentioning

confidence: 99%

Eating behavior as a new frontier in memory research

Seitz

Tomiyama

Blaisdell

2021

Neuroscience & Biobehavioral Reviews

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The study of memory is commonly associated with neuroscience, aging, education, and eyewitness testimony. Here we discuss how eating behavior is also heavily intertwined-and yet considerably understudied in its relation to memory processes. Both are influenced by similar neuroendocrine signals (e.g., leptin and ghrelin) and are dependent on hippocampal functions.While learning processes have long been implicated in influencing eating behavior, recent research has shown how memory of recent eating modulates future consumption. In humans, obesity is associated with impaired memory performance, and in rodents, dietary-induced obesity causes rapid decrements to memory. Lesions to the hippocampus disrupt memory but also induce obesity, highlighting a cyclic relationship between obesity and memory impairment.Enhancing memory of eating has been shown to reduce future eating and yet, little is known about what influences memory of eating or how memory of eating differs from memory for other behaviors. We discuss recent advancements in these areas and highlight fruitful research pursuits afforded by combining the study of memory with the study of eating behavior.

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Early postnatal exposure to a cafeteria diet interferes with recency and spatial memory, but not open field habituation in adolescent rats

Cited by 5 publications

References 91 publications

Behavioural alterations induced by intermittent ethanol intake and noise exposure in adolescent rats

Behavioural alterations induced by intermittent ethanol intake and noise exposure in adolescent rats

The Effects of Stress and Diet on the “Brain–Gut” and “Gut–Brain” Pathways in Animal Models of Stress and Depression

Eating behavior as a new frontier in memory research

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