Early Postoperative Outcomes of Breast Cancer Surgery in a Developing Country

Rizvi, Farrukh Hassan; Khan, Muhammad Kashif; Almas, Talal; Ullah, Mujib; Shafi, Adil; Murad, Muhammad Faisal; Ali, Aabid; Nadeem, Faisal

doi:10.7759/cureus.9941

Cited by 11 publications

(14 citation statements)

References 13 publications

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“…The rarest complications were represented by the wound infection: 2 cases (10.5%) and the axillary lymphocele: 1 case (5.3%). The results obtained were partially correlated with recent data from the literature indicating seroma as the most common postoperative complication followed by wound infection, hematoma and flap necrosis (16). Of note is the absence of seroma in patients who underwent surgery, which can be explained by the use of drainage tubes at the end of the surgery.…”

Section: Resultssupporting

confidence: 80%

Impact of modern personalized treatment of breast cancer on surgical attitude and outcomes

et al. 2021

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Section: Resultssupporting

confidence: 80%

Impact of modern personalized treatment of breast cancer on surgical attitude and outcomes

et al. 2021

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“…On the contrary, the rate of surgical site infections, 14.9% in our study, was higher in our patient population compared to published reports which ranged between 2 and 6% [24][25][26]. Reports indicated older age, Hypertension, high volume of drainage output, serum protein concentration, longer operative time, and lack of patient-controlled analgesia to be risk factors for seroma formation [23,[27][28][29]. In contrast, in our study, we found a higher seroma rate in patients with a history of diabetes, neoadjuvant chemotherapy, 10 or more lymph node dissection and a higher BMI (> 24 kg/m 2 ).…”

Section: Discussioncontrasting

confidence: 78%

“…Reports indicated older age, Hypertension, high volume of drainage output, serum protein concentration, longer operative time, and lack of patient-controlled analgesia to be risk factors for seroma formation [ 23 , 27 – 29 ]. In contrast, in our study, we found a higher seroma rate in patients with a history of diabetes, neoadjuvant chemotherapy, 10 or more lymph node dissection and a higher BMI (> 24 kg/m 2 ).…”

Section: Discussionmentioning

confidence: 99%

Experience with modified radical mastectomy in a low-income country: a multi-center prospective observational study

et al. 2021

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Background Modified radical mastectomy is the procedure of choice in centers with little to no radiotherapy services. Studying the in-hospital outcome and complications associated with the procedure is important in low-income countries. Methods This is a multi-center prospective observational study involving all patients operated with modified radical mastectomy with curative intent. Results A total of 87 patients were studied with 10.3% of which were male and 54% were between the age of 30–49 years. Clinical stage IIB and IIIA were reported in 33 (37.9%) and 25 (28.7%) respectively and 62.1% had clinically positive lymph nodes at presentation. All of the studied patients underwent curative surgery, with an average lymph node dissection of 10.2 ± 0.83. Seroma rate was 17.2% and was significantly associated with diabetes (AOR: 6.2 (CI 1.5–8.7)) and neoadjuvant chemotherapy (AOR: 8.9 (CI 1.2–14.2)). Surgical site infection occurred in 14.9% and was significantly associated with Retroviral infections (AOR: 4.2 (CI 2.1–5.8)) and neoadjuvant chemotherapy (AOR: 1.8 (CI 1.3–3.9)). No in-hospital mortality occurred during the course of the study. Conclusion Seroma rate was lower than published studies while surgical site infections rate was higher. Neoadjuvant chemotherapy was associated with increase in seroma and surgical site infection rates. Additionally, diabetes increased the rate of seroma. Surgical site infections were higher in patients with retroviral infections.

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“…Since the 2015 Lancet Commission on Global Surgery, a number of studies on the feasibility and safety of surgical procedures for several cancers including orofacial, gastrointestinal, urological, gynecological, breast, brain, and spine tumors have been performed in countries including Egypt, India, Nigeria, Pakistan, and Taiwan. [22][23][24][25][26][27][28][29][30][31][32][33][34][35][36] It is notable that most of these studies were performed at a single institution, with multicenter collaborative studies being rare. Surgical interventions described mostly include resections which aim to maximize overall survival and progression-free survival such as pancreaticoduodenectomy, gastrectomy, hepatectomy, cytoreductive surgery, laparoscopic colorectal surgery, radical cystectomy, partial nephrectomy, and brain and spine tumor removal.…”

Section: Local Innovations and Feasibility Studiesmentioning

confidence: 99%

Global cancer surgery in low‐resource settings: A strengths, weaknesses, opportunities, and threats analysis

Sadler

Torio

Golby

2023

Cancer

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Global cancer surgery is an essential and complex component of oncologic care. This study aims to describe global cancer surgery literature since the 2015 Lancet Commission on Global Surgery and Cancer Surgery and perform a strengths, weaknesses, opportunities, and threats (SWOT) analysis. A systematic search was performed in PubMed of global cancer surgery articles. Themes were extracted from the included studies based on the following criteria: (1) performed in low‐ or low‐middle–income countries, (2) published during or after 2015, (3) published in peer‐reviewed journals, (4) written in the English language, and (5) accessible to the authors. Themes were further grouped into strengths, weaknesses, opportunities, and threats (SWOT analysis). The search strategy identified 154 articles published from 1992 to 2022. Forty‐six articles were included in the qualitative synthesis and SWOT analysis. Recurring themes included local epidemiologic studies, local innovations and feasibility studies, prioritizing quality of life outcomes, multidisciplinary team approaches, limited resources, health system gaps, lack of economic analyses, diverse cancer management strategies and priorities, inter‐setting collaboration, research expansion, the coronavirus disease 2019 pandemic, and unchecked technological advancements. These strengths, weaknesses, opportunities, and threats were described and related to the themes of research, surgical systems strengthening, economics and financing, and political framing of the 2015 Lancet Commission on Global Cancer Surgery. SWOT analyses of global cancer surgery may be helpful in suggesting future strategies for this expanding field. Plain language summary Cancer surgery is a resource‐intensive yet essential component of cancer care. In the face of projected growth of cancer burden, the present gap in cancer surgery care in low‐resource settings with stressed health care and surgical infrastructure risks further exacerbation. We present a strengths, weaknesses, opportunities, and threats analysis of recent global cancer surgery literature pertaining to low‐resource settings.

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Early Postoperative Outcomes of Breast Cancer Surgery in a Developing Country

Cited by 11 publications

References 13 publications

Impact of modern personalized treatment of breast cancer on surgical attitude and outcomes

Impact of modern personalized treatment of breast cancer on surgical attitude and outcomes

Experience with modified radical mastectomy in a low-income country: a multi-center prospective observational study

Global cancer surgery in low‐resource settings: A strengths, weaknesses, opportunities, and threats analysis

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