Early prediction of delayed cerebral ischemia in subarachnoid hemorrhage based on quantitative EEG: A prospective study in adults

Continuous EEG Monitoring for Early Detection of Delayed Cerebral Ischemia in Subarachnoid Hemorrhage: A Pilot Study

“…EEG was able to detect ischemia several hours prior to clinical deterioration and 44 h prior to detection of ischemic lesions on CT scan. Other small studies have investigated qEEG features for detection of DCI in 19 [14], 9 [15], and 6 [17] aSAH patients. The relative alpha variability, the ADR, and alpha power, respectively, were described as the most useful qEEG features for detection of DCI.…”

“…Secondly, in our study, an algorithm was used to select the EEG epoch that contained the least amount of artifacts [21]. Previous studies performed this epoch selection manually, except for one recent study that also used an automatic algorithm for artifact rejection [17]. Manual selection might impede the objectivity of the data analysis.…”

“…Some studies investigating the relation between DCI and continuous EEG (cEEG) monitoring have suggested that cEEG can assist in early detection of DCI [13][14][15][16][17]. Only two studies elaborated on the possibility to detect compromised neuronal function prior to clinical deterioration [16,17]. One study only included patients at high risk for DCI, based on the modified Fisher scale.…”

“…It was found that in three out of eight patients, changes in cEEG occurred prior to clinical changes [16]. The second study used cEEG monitoring in six DCI patients and was able to detect DCI prior to changes in transcranial Doppler (TCD) [17]. In this study, we explore if cEEG can be used as a diagnostic tool for detection of DCI prior to onset of clinical symptoms and/or ischemia development on CT.…”

Continuous Electroencephalography Monitoring in Adults in the Intensive Care Unit

“…Several studies have investigated the prognostic significance of EEG recordings in patients with subarachnoid hemorrhage [9,10,[26][27][28]. Claassen et al reported that outcome was poor (modified Rankin Scale 4 to 6) in all patients with absent EEG reactivity, GPDs, or BIPDs, and in 92% of patients with NCSE [33].…”