Early Primary Repair of Tetralogy of Fallot in Neonates and Infants Less Than Four Months of Age

Tamesberger, Melanie; Lechner, Evelyn; Mair, Rudolf; Hofer, Anna; Sames-Dolzer, Eva; Tulzer, Gerald

doi:10.1016/j.athoracsur.2008.07.019

Cited by 111 publications

(81 citation statements)

References 21 publications

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“…Our Kaplan-Meier freedom from any reoperation of 85.2 AE 13.6% at 5 years, as well as a mortality of 0%, match favorably with contemporary results [2,8].…”

Section: Discussionsupporting

confidence: 87%

“…TOF is a complex congenital malformation with excellent early and late outcome after intracardiac repair [2,7,8]. With increasing numbers of patients with corrected TOF surviving into adulthood [9][10][11], attention is being diverted to residual lesions, hitherto considered benign, which can influence the longevity and quality of life of these patients, the aim being to achieve a survival and quality of life comparable to normal population.…”

Section: Discussionmentioning

confidence: 99%

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Realignment of the ventricular septum using partial direct closure of the ventricular septal defect in Tetralogy of Fallot

Till

Dave

Comber

et al. 2011

European Journal of Cardio-Thoracic Surgery

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“…Our Kaplan-Meier freedom from any reoperation of 85.2 AE 13.6% at 5 years, as well as a mortality of 0%, match favorably with contemporary results [2,8].…”

Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Realignment of the ventricular septum using partial direct closure of the ventricular septal defect in Tetralogy of Fallot

Till

Dave

Comber

et al. 2011

European Journal of Cardio-Thoracic Surgery

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show abstract

“…The only curative therapy for TOF today is corrective surgery, and most centres prefer to operate on children aged three to six months, although some centres advocate primary complete repair at diagnosis, even within the first few days of life [8,9]. TOF corrective surgery is associated with a high success rate, most patients undergoing complete repair have an uncomplicated postoperative recovery and are discharged within a week of surgery [1].…”

Section: Discussionmentioning

confidence: 99%

Effect of Preoperational Mechanical Ventilation on Short-Term Postoperative Outcomes in Patients with Severe Tetralogy of Fallot

Dong

Wang

et al. 2012

Heart, Lung and Circulation

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“…As for repair in the neonatal age, there are controversial opinions [37]. Patients under 3 months of age are linked to longer hospitalization and ventilation with the increased need of inotropic agents compared to the population over 6 months of age [38].…”

Section: Role Of Timing and Techniques Of Surgical Repairmentioning

confidence: 99%

Late arrhythmia in patients with repaired tetralogy of Fallot: who is at risk?

Grigaliūnas

Gumbienė

Valevičienė

et al. 2015

Seminars in Cardiovascular Medicine

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SummaryTetralogy of Fallot (TOF) is the most common cause of cyanotic congenital heart defect. Over the last century, the life expectancy of TOF patients has significantly improved. This, however, has brought new challenges both to patients and their health-care providers, the main of them being late arrhythmia. Ironically, late arrhythmia is predominantly generated due to the fibrotic scars caused by the life-saving surgical repair. Once the first two mainly arrhythmia-free decades after the repair pass, the risk of developing late arrhythmia and, therefore, SCD becomes substantial. Consequently, young adults with repaired Tetralogy of Fallot (rTOF) require careful outpatient monitoring.There have been many attempts to predict the risk of life-threatening arrhythmia in rTOF patients. This has led to the defining of various risk factors, ranging from the widely used QRS prolongation to novel predictors, derived from cardiac magnetic resonance (CMR) based anatomical findings (left ventricular dyssynchrony indexes, right ventricular output tract akinetic length, right ventricular mass-to-volume ratio). The latter predictors have recently established CMR as a tool of high significance in evaluation of rTOF patients.Although the role of Holter monitoring findings in rTOF patient-assessment remains unclear, it may be useful in those who are 25 years and older. Implantable cardioverter-defibrillator (ICD) implantation is the first-line treatment for secondary prevention of sudden cardiac death (SCD). rTOF patients suffer from the highest rate of inappropriate and the lowest rate of appropriate ICD shocks, when compared to other congenital heart diseases. As a consequence, ICD implantation for primary SCD prevention should be carefully weighed. Catheter-based ablation therapy leads to high rate of initial success when abolishing monomorphic ventricular tachycardia and intra-atrial reentrant tachycardia, however recurrence rates remain high. Seminars in Cardiovascular Medicine

show abstract

Early Primary Repair of Tetralogy of Fallot in Neonates and Infants Less Than Four Months of Age

Cited by 111 publications

References 21 publications

Realignment of the ventricular septum using partial direct closure of the ventricular septal defect in Tetralogy of Fallot

Realignment of the ventricular septum using partial direct closure of the ventricular septal defect in Tetralogy of Fallot

Effect of Preoperational Mechanical Ventilation on Short-Term Postoperative Outcomes in Patients with Severe Tetralogy of Fallot

Late arrhythmia in patients with repaired tetralogy of Fallot: who is at risk?

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