Early Prognosis of Severe Traumatic Brain Injury in an Urban Argentinian Trauma Center

Petroni, Gustavo; Quaglino, Marta Beatriz; Lujan, Silvia; Kovalevski, Leandro; Rondina, Carlos; Videtta, Walter; Carney, Nancy; Temkin, Nancy; Chesnut, Randall M.

doi:10.1097/ta.0b013e3181ce1eed

Cited by 40 publications

(29 citation statements)

References 19 publications

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“…Thus, for LMICs, the study provided concrete information on which to base resource-allocation decisions, and documented the clinical success of a treatment approach that is sustainable in low-resource environments. Sufficiently skilled clinical staff with a better organized protocol of care could produce good recovery results in the intensive care unit (ICU) without data from an ICP monitor by using clinical assessment to manage intracranial hypertension [53][54][55][56] .…”

Section: Lessons Learned From Clinical Neurotrauma Researchmentioning

confidence: 99%

Global neurotrauma research challenges and opportunities

Rubiano

Carney

Chesnut

et al. 2015

Nature

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426

277

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Section: Lessons Learned From Clinical Neurotrauma Researchmentioning

confidence: 99%

Global neurotrauma research challenges and opportunities

Rubiano

Carney

Chesnut

et al. 2015

Nature

Self Cite

426

277

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“…Severe TBI is defined as TBI with initial Glasgow coma scale ≤ 8 after resuscitation. It threatens life on short term and can lead to persisting neurologic disability which puts a heavy socio-economic burden on the entire society, families and individuals [1]- [11]. Severe TBI is the 3 rd leading cause of death in industrialized countries and according to the WHO it might become the leading cause of death and disability worldwide by the year 2020 [1] [8].…”

Section: Introductionmentioning

confidence: 99%

Epidemiological Analysis of 135 Cases of Severe Traumatic Brain Injury Managed at a Surgical Intensive Care Unit

Ndoumbe¹,

Edu²,

Simeu³

et al. 2018

OJMN

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This study was a retrospective analysis of the epidemiologic profile of severe traumatic brain injuries managed at the surgical intensive care unit of the University Hospital Center of Yaoundé, Cameroon, between January 2011 and December 2015. All the patients admitted at the surgical intensive care unit for a traumatic brain injury with an initial Glasgow coma scale score ≤ 8 were included. One hundred and thirty-five cases were enrolled. One hundred and fourteen were males and 21 were females. Their mean age was 32.75 years. Forty-four patients were aged between 16 to 30 years. Road traffic accidents represented the first mode of injury with 101 cases and most of the patients were pedestrians hit by a car. Pupils and students were the most involved. Twenty-three patients had additional extracranial injury. On admission, 97 (71.85%) patients had GCS 7-8. A brain CT scan was done for 115 patients. Intracranial and intracerebral hemorrhages were the most frequent radiological findings with 57 cases. The overall mortality was 32.59% with 44 deaths. Thirty-two of the deaths occurred in patients with GCS 7 -8 on admission. Ninety-one (67.40%) patients survived, 74 (54.81%) had persisting disabilities, while only 17 (12.59%) recovered fully. The following factors had an impact on the outcome: GCS at admission, pupillary anomalies, length of hospital stay, endotracheal intubation and surgery. Severe TBI remains a heavy socio-economic burden worldwide. In Cameroon where the health system is poorly organized, the outcome of individuals who sustained a severe TBI was dismal.

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“…No study has reported the prevalence in Africa. Only 2 of the 21 studies were from developing countries (7.33% from Kelantan, Malaysia and 0.68% from Rosario, Argentina) (Petroni et al, 2010;Selladurai et al, 1992) The overall prevalence in developing countries is 6.3%, which is higher than the overall prevalence of 2.8% in developed countries. The quality and availability of emergency and intensive care services differs among different regions.…”

Section: Locationmentioning

confidence: 77%

“…After 2324 duplications removed, 1930 additional articles were excluded on the basis of their titles or abstracts, resulting in the full text of 341 articles being examined. Finally, 20 articles reporting 21 cohort studies were included in the present analysis (Andriessen et al, 2011;Fearnside, Cook, McDougall, & McNeil, 1993;Foulkes, Eisenberg, Jane, Marmarou, & Marshall, 1991;Gomez et al, 2000;Heiden, Small, Caton, Weiss, & Kurze, 1983;Jourdan et al, 2013;Judson, Cant, & Shaw, 1990;Lannoo et al, 2000;Mamelak, Pitts, & Damron, 1996;; L. S. Myburgh et al, 2008;Nordstrom, Messeter, Sundbarg, & Wahlander, 1989;Pang et al, 2007;Petroni et al, 2010;Rusnak, Janciak, Majdan, Wilbacher, & Mauritz, 2007;Selladurai, Jayakumar, Tan, & Low, 1992;Stranjalis et al, 2008;Turazzi, Bricolo, & Pasut, 1984;Turazzi, Bricolo, Pasut, & Formenton, 1987). A flow diagram of the selection process is presented in Fig.…”

Section: Resultsmentioning

confidence: 99%

“…The included studies were mostly from America and Europe; of 21 studies, 11 were from Europe, 3 from the United States, and 1 was carried out in both. Only two studies were from Asia (7.33% from Kelantan, Malaysia and 6.60% from Singapore) (Pang et al, 2007;Selladurai et al, 1992) and one from Latin America (0.68% from Rosario, Argentina) (Petroni et al, 2010). No study has reported the prevalence in Africa.…”

Section: Locationmentioning

confidence: 99%

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Prevalence of persistent vegetative state in patients with severe traumatic brain injury and its trend during the past four decades: A meta-analysis

Tang

Jin

Gao

et al. 2017

NRE

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Abstract. BACKGROUND:Estimating the prevalence of persistent vegetative state (PVS) following severe traumatic brain injury (sTBI) and its change over time is important for the study of the disease. OBJECTIVE: To estimate the prevalence of PVS at six months after sTBI and its trend over the past four decades, and to explore the effect of demographic data, such as age and sex, on the prevalence of PVS. METHOD: Observational studies presenting the prevalence of PVS or the number of patients with PVS at six months after sTBI were included in the analysis. The overall prevalence and prevalence within pre-defined time intervals were calculated and meta-regression analysis was performed to assess the effect of age, gender, and time on the prevalence. RESULTS: Twenty articles reporting 21 cohort studies were included. The overall prevalence of PVS at six months after injury was 2.77% (95% CI 0.0204-0.0375). There was no statistically significant trend towards time (P = 0.77). And we found no differences in prevalence according to age (P = 0.68) and gender (P = 0.57). CONCLUSIONS: Prevalence of PVS at six months after sTBI has no significant change over the past four decades. Age and gender do not seem to have a significant effect on the prevalence.

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Early Prognosis of Severe Traumatic Brain Injury in an Urban Argentinian Trauma Center

Cited by 40 publications

References 19 publications

Global neurotrauma research challenges and opportunities

Global neurotrauma research challenges and opportunities

Epidemiological Analysis of 135 Cases of Severe Traumatic Brain Injury Managed at a Surgical Intensive Care Unit

Prevalence of persistent vegetative state in patients with severe traumatic brain injury and its trend during the past four decades: A meta-analysis

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