Early psoriatic arthritis

Loginova, E. Y.; Коротаева, Т. В.

doi:10.14412/1995-4484-2008-490

Cited by 5 publications

(3 citation statements)

References 39 publications

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“…«Золотым стандартом» диагностики ПсА, в том числе и на ранней стадии, считают критерии CASPAR (ClASsification criteria for Psoriatic ARthritis) [4], которые позволяют установить диагноз ПсА, даже при на-личии ревматоидного фактора (РФ) и отсутствии псориаза [5]. Заметную роль в ранней диагностике ПсА играют та-кие инструментальные методы, как рентгенография, ульт-развуковое исследование (УЗИ), магнитно-резонансная томография (МРТ) суставов и позвоночника, а также сцинтиграфия скелета [6,7].…”

Section: Osteoarticular Injury In Psoriatic Patients According To Theunclassified

Diagnostic delay of more than 6 months contributes to poor radiographic and functional outcome in psoriatic arthritis

2014

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Objectives(1) To investigate the demographic and clinical characteristics contributing to the delay from symptom onset to the first visit to a rheumatologist; (2) to compare clinical, radiographic and patient-reported outcome measures of those who saw a rheumatologist early in their disease course with those who were diagnosed later.MethodsAll psoriatic arthritis (PsA) patients, fulfilling CASPAR criteria, with an average disease duration of >10 years were invited for detailed clinical evaluation. The total lag time from symptom onset to their first rheumatological encounter was studied. The data were extracted from the referral letters and medical records. Patients were classified as early consulters or late consulters depending on whether they were seen by a rheumatologist within or beyond 6 months of symptom onset.Results283 PsA patients were studied. Median lag time from the disease onset to the first rheumatological assessment of the cohort was 1.00 years (IQR 0.5–2). 30% (n=86), 53% (n=149) and 71% (n=202) of the cohort were seen by a rheumatologist within 6 months, 1 and 2 years of symptom onset, respectively. PsA patients with low education status (OR 2.09, p=0.02) and Body Mass Index (OR 0.92, p=0.01) were significantly more likely to have a diagnostic delay of >2 years. On multiple stepwise regression analysis, the model predicted significant association of late consulters with the development of peripheral joint erosions (OR 4.25, p=0.001) and worse Health Assessment Questionnaire scores (OR 2.2, p=0.004).ConclusionsEven a 6-month delay from symptom onset to the first visit with a rheumatologist contributes to the development of peripheral joint erosions and worse long-term physical function.

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Section: Osteoarticular Injury In Psoriatic Patients According To Theunclassified

Diagnostic delay of more than 6 months contributes to poor radiographic and functional outcome in psoriatic arthritis

2014

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“…[23] показали, что дактилит не только служит специфичным признаком ПсА, но и ассоциируется с быстрым рентгено-логическим прогрессированием заболевания, являясь маркером неблагоприятного прогноза. Дактилит, по дан-ным разных авторов, наблюдается у 29-37% больных рПсА [24,25]. При анализе взаимосвязи дактилита с кли-нико-лабораторными показателями при рПсА нами вы-явлена их ассоциация с деструктивным процессом в сус-тавах кистей и стоп, высокой воспалительной активно-стью заболевания и энтезитом по данным МРТ.…”

Section: д и н а м и к а в а р и а н т о в с у с т а в н о г о с и н unclassified

“…В число основных проявлений ПсА, наряду с артритом, спондилитом и дактилитом, входит и энтезит [25,27,28]. Для количественной оценки энтезита широко используется индекс MASES, который первоначально был разработан для АС.…”

Section: д и н а м и к а в а р и а н т о в с у с т а в н о г о с и н unclassified

Clinical Heterogeneity of Early Psoriatic Arthritis

Бадокин¹,

Трошкина²

2016

RJTAO

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Early prescription of biological agents for immune-mediated inflammatory diseases: opportunities and prospects. An expert’s opinion

Абдулганиева

Бакулев

Belousova

et al. 2020

Sovremennaâ revmatologiâ

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Psoriasis (Ps), psoriatic arthritis (PsA), and inflammatory bowel diseases (IBDs) are characterized by a progressive course and frequently lead to disability; therefore, their early diagnosis with the assessment of a clinical phenotype and unfavorable prognostic factors and the timely initiation of therapy are important tasks. The paper provides the experts agreed opinion on the definition of the early stage of Ps, PsA, and IBDs, the goals of therapy and main unfavorable prognostic factors for the course of these diseases and gives the rationale for the early use of biological agents in patients with immune-mediated inflammatory diseases.

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Early psoriatic arthritis

Cited by 5 publications

References 39 publications

Diagnostic delay of more than 6 months contributes to poor radiographic and functional outcome in psoriatic arthritis

Diagnostic delay of more than 6 months contributes to poor radiographic and functional outcome in psoriatic arthritis

Clinical Heterogeneity of Early Psoriatic Arthritis

Early prescription of biological agents for immune-mediated inflammatory diseases: opportunities and prospects. An expert’s opinion

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