Background The management of bone infections has always posed a challenge in the field of orthopedics, and geriatric knee joint bone infections are even more difficult. In this study, we aimed to assess the clinical efficacy of using antibiotic-loaded bone cementcombined with tibial intramedullary nail as a last resort treatment option for geriatric knee joint bone infection patients.
Methods The retrospective study was conducted on 11 elderly patients with knee joint bone infection. The cohort comprised 3 male and 8 female patients, with an average age of 74.27±3.47years. Of these patients, 4 patients experienced reinfection after knee revision replacement, while 7 patients had knee joint bone infection.After stage-1 infection control, all patients underwent a stage-2 treatment using antibiotic-loaded bone cement combined with tibial intramedullary nail as the ultimate treatment approach.
Results All patients’ infections were effectively controlled. The average length of bone defect after debridement was 12.09±1.22cm. The duration of the stage-2 operation averaged180.27±11.06minutes. Postoperatively, there was no significant discrepancy in the length of the patients’ lower limbs. All patients experienced a significant enhancement in knee joint function, as indicated by the decrease in WOMAC scores from 141.45±11.75preoperatively to 79.09±0.34postoperatively. Pain levels saw a profound reduction, plummeting from 26.27 ± 2.45 to a non-existent 0.00 ± 0.00. Additionally, there was a substantial improvement in performing daily activities, rising impressively from 59.09 ± 0.34 to 100.55 ± 8.37. However, an increase in joint stiffness was noted, worsening slightly from 15.45 ± 1.63 to 20.00 ± 0.00.One case of peri-implant fracture occurred.
Conclusion Antibiotic-loaded bone cement combined with tibial intramedullary nailing as last resort treatment can be considered as an alternative surgical option for elderly patients with knee joint bone infection who have experienced multiple failed operations and long-term knee stiffness.