Early results of aortic valve reconstruction with stentless glutaraldehyde treated autologous pericardial valve

Mittal, Chander Mohan; Talwar, Sachin; Devagourou, Velayoudam; Kothari, Shyam Sunder; Kumar, Amit

doi:10.1007/s12055-009-0055-3

Cited by 6 publications

(5 citation statements)

References 22 publications

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“…In a long-term study of patients undergoing mAVR, the linear zed rates per 100 patients years of follow-up were embolism 0.25, paravalvular leakage 0.25, prosthetic endocarditic 0.25 and reoperation 0.50 [10]. This compares favorably with the results of pericardial AVR [2][3][4]. Despite a reoperation at 10 years, our patient was in NYHA class I/II at follow up and the reoperation was safe.…”

Section: Discussionmentioning

confidence: 56%

“…Besides superior hemodynamics compared to a mechanical valve, it is more resistant to infection and avoids the long term hazards of anticoagulation [6]. Excellent mid and long-term results have been reported [2][3][4][5]. However, all patients undergoing this operation are expected to require a re-operation due to calcification and structural deterioration of the valve [3].…”

Section: Discussionmentioning

confidence: 99%

“…The procedure has been demonstrated to be an inexpensive substitute to mAVR and avoids long term costs and compliance associated with anticoagulation, more so in the third world [1,2]. Acceptable midterm and long term results have been reported [2][3][4][5]. However, it is not expected to be a permanent substitute because the pericardium is expected to undergo degenerative changes in the mid to long term.…”

Section: Introductionmentioning

confidence: 99%

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Pathological Changes in the Autologous Pericardial Aortic Valve at 10 Years

Talwar¹,

Makhija²,

Dhawan³

et al. 2017

BJSTR

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Section: Discussionmentioning

confidence: 56%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Pathological Changes in the Autologous Pericardial Aortic Valve at 10 Years

Talwar¹,

Makhija²,

Dhawan³

et al. 2017

BJSTR

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“…Alternatively, a trileaflet valve can be fashioned from autologous pericardium. 27,28 Both these surgical techniques require patience and skill. These can be combined with MV repair.…”

Section: Associated Lesionsmentioning

confidence: 99%

Surgical Options in Rheumatic Mitral Valve Disease in Children

Kumar¹

2014

World J Pediatr Congenit Heart Surg

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In children with rheumatic heart disease, conservative valve surgery is the best option whenever feasible. Surgeons must develop an attitude and interest in valve repair techniques that can be easily learned. Patients who undergo valve repair at an early age are at risk of requiring additional surgery over time. Mechanical valve replacement, nonetheless, should be reserved for situations where more conservative approaches are not feasible.

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“…However, for aortic valve disease, aortic msalinger@northshore.org valve replacement is a commonly performed procedure and provides satisfactory long term results [1]. Replacement with mechanical prosthesis in a young patient has drawbacks of long-term anticoagulation and definite risk for thromboembolic complications [2]. Bioprosthesis implantation is the preferred choice for AVR in the elderly as a result of the shorter life expectancy and reduced need of anticoagulation.…”

Section: Introductionmentioning

confidence: 99%

Early Experience in Aortic Valve Reconstruction with Autologous Pericardium for Aortic Valve Insufficiency

Hassanein¹,

Zayed²

2017

AJCTS

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Objective: Several authors have reported good results with the use of autologous treated pericardium for aortic valve reconstruction with good results specially the current series of Ozaki, so we decided to start our learning curve in this type of surgery for its benefits and to avoid the cost and potential complications that may be resulted from aortic valve replacement.Methods: Between August 2013 and November 2015, 43 patients were scheduled for aortic valve reconstruction using gluataraldehyde treated autologous pericardium. They were isolated aortic lesions or associated with repairable mitral or mitral and tricuspid valve lesion (26 patients were pure aortic regurge, 8 patients were aortic regurge + mild to moderate stenosis, 5 patients were aortic valve lesion associated with mitral regurge and 4 patients were aortic lesions associated with mitral and tricuspid regurge). Their mean age was 30.4 ± 6.7 and male/female was 25/18. We used Gaspayran formula to fabricate new pericardial leaflet, all patients were evaluated by transesophygeal echo before discharging from the operating room.Results: 4 patients out of 43 patients have undergone aortic valve replacement (2 of them because of mitral valve repair failed and the other 2 because of thickened pericardium and adhesion) aortic valve reconstruction was done successfully in the remaining patients (39 patients).There were no hospital deaths, transthoracic echo before discharge from the hospital revealed no regurge and no significant pressure gradient, also follow up echo for a mean period 21.5 ± 6.9 months revealed stable aortic valve function with no significant pressure gradient or significant regurge. Conclusion:Aortic valve reconstruction with treated autologous pericardium is feasible with acceptable hemodynamic. The cornerstone of this surgery is perfect sizing and fabricating the new pericardial aortic leaflets and precise suturing methods.(n = Non-coronary cusp, r = right coronary cusp, l = left coronary cusp)

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Early results of aortic valve reconstruction with stentless glutaraldehyde treated autologous pericardial valve

Cited by 6 publications

References 22 publications

Pathological Changes in the Autologous Pericardial Aortic Valve at 10 Years

Pathological Changes in the Autologous Pericardial Aortic Valve at 10 Years

Surgical Options in Rheumatic Mitral Valve Disease in Children

Early Experience in Aortic Valve Reconstruction with Autologous Pericardium for Aortic Valve Insufficiency

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