Early risk stratification of patients with major trauma requiring massive blood transfusion

Rainer, Timothy Hudson; Ho, Anthony M.‐H.; Yeung, John H.K.; Cheung, Nam Sang; Wong, Raymond Siu Ming; Tang, Ning; Ng, SM; Wong, George Kwok Chu; Lai, Paul B.S.; Graham, Colin A.

doi:10.1016/j.resuscitation.2011.02.016

Cited by 118 publications

(104 citation statements)

References 27 publications

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“…[18] Consistent with previous studies, blood transfusion and surgery were associated with improved survival. [6,18,19] ROSC was lower (14.9%) compared to reported rate of 26%, in previous study. [13] The overall survival in this study (2.4%) was higher than 1.7%, reported in a recent Australian study.…”

Section: Resultscontrasting

confidence: 55%

Cardiopulmonary resuscitation of out-of-hospital traumatic cardiac arrest in Qatar: A nationwide population-based study

Irfan

Consunji

El‐Menyar

et al. 2017

International Journal of Cardiology

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Section: Resultscontrasting

confidence: 55%

Cardiopulmonary resuscitation of out-of-hospital traumatic cardiac arrest in Qatar: A nationwide population-based study

Irfan

Consunji

El‐Menyar

et al. 2017

International Journal of Cardiology

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“…However, some studies showed no relationship between transfusion and postoperative complications [20,21]. However, transfusions are an essential treatment method in cases of massive bleeding [22]. These controversial findings imply that the Hb level can be used as an indicator for transfusion [9].…”

Section: Discussionmentioning

confidence: 99%

Impact of perioperative hemoglobin levels on postoperative outcomes in gastric cancer surgery

et al. 2012

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Background The aim of this study was to evaluate the association of postoperative blood transfusion and anemia with postoperative outcomes in gastric cancer surgery. Methods We enrolled 588 patients who had undergone curative resection for gastric cancer. Input variables for risk assessment consisted of 3 categories: patient demographics, surgical and pathological factors, and anemia-related factors. Postoperative outcomes included 30-day morbidity and mortality. Univariate and multivariate analyses were performed to identify risk factors influencing postoperative complications. Results The rate of total complications was 19.0 %. Comorbidity, lowest hemoglobin (Hb) level from the operative day up to postoperative day 7 (LOW-Hb), the percentage of drop in Hb level on postoperative day 2 (POD2-Hb change), and postoperative transfusion were independent risk factors in the multivariate analysis, with LOW-Hb and postoperative transfusion found to be the most significant factors. When LOW-Hb was C9.0 g/dL, postoperative complications were higher in the transfused group than in the non-transfused group (60.0 vs. 14.2 %, respectively, p = 0.024), but when LOW-Hb was\9.0 g/dL, postoperative complications were not different between the 2 groups (44.6 vs. 37.5 %, p = 0.525). ConclusionThe lowest postoperative Hb level and postoperative transfusion were the most significant risk factors for postoperative complications in gastric cancer surgery.

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“…Meanwhile, we have in place a '1:1' policy for serious trauma patients requiring massive blood transfusion at the Prince of Wales Hospital, having analysed all '1:1' Figure 2 Kaplan-Meier survival curves of trauma patients [12] requiring massive transfusion, for high (thick) and low (thin) fresh frozen plasma: packed red blood cell ratio; a) ratio not treated as a time-dependent covariate (p < 0.001); b) ratio treated as a time-dependent covariate (p = 0.17). studies and reasoned that massive loss of blood needs replacement with its equivalent (roughly equal number of units of PRBC, FFP and platelets) [2,13,14]. One must always apply common sense.…”

Section: (Common) Sense and Sensibilitymentioning

confidence: 99%

Understanding immortal time bias in observational cohort studies

Dion²,

et al. 2012

Anaesthesia

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Early risk stratification of patients with major trauma requiring massive blood transfusion

Cited by 118 publications

References 27 publications

Cardiopulmonary resuscitation of out-of-hospital traumatic cardiac arrest in Qatar: A nationwide population-based study

Cardiopulmonary resuscitation of out-of-hospital traumatic cardiac arrest in Qatar: A nationwide population-based study

Impact of perioperative hemoglobin levels on postoperative outcomes in gastric cancer surgery

Understanding immortal time bias in observational cohort studies

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