Early sex-specific modulation of the molecular clock in trauma

Abstract

Epidemiologic study, level IV.

Epidemiology of trauma in France: mortality and risk factors based on a national medico-administrative database

“…Our findings are in line with those of a meta-analysis showing that males are associated with an increased risk of mortality after trauma [22]. In general, male over mortality is found in physiologic and most pathologic states [1][2][3]21].…”

“…Indeed, extremity injuries were more frequent in females, while head injuries were predominant in males. Differences in outcomes between gender are quite complex to understand; they can be due to societal factors, gene differences, and hormone production [21]. Our findings are in line with those of a meta-analysis showing that males are associated with an increased risk of mortality after trauma [22].…”