Early Stone Manipulation in Urinary Tract Infection Associated with Obstructing Nephrolithiasis

Swonke, Megan L; Mahmoud, Alì Mokhtar; Farran, Elias J; Dafashy, Tamer J.; Kerr, Preston; Kosarek, Christopher D.; Sonstein, Joseph

doi:10.1155/2018/2303492

Cited by 3 publications

(1 citation statement)

References 18 publications

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“…With the popularity of this technology clinically, more and more complications have been recognized by clinicians. SIRS is one of complications receiving numerous attentions from health care providers, and it's one of the most important and timely clinical manifestations for SIRS (15,16). Therefore, understanding the risk factors affecting postoperative fever after PCNL has important guiding significance for preventing SIRS after PCNL.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for the fever after percutaneous nephrolithotomy: a retrospective analysis

et al. 2020

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Background: It's very common to see the onset of fever after percutaneous nephrolithotomy (PCNL), it's necessary to analyze the risk factors for the fever following PCNL, and to provide evidence for infection prevention after PCNL.Methods: A total of 546 adult PCNL patients were included as study subjects and retrospective studies were performed. We collected clinical data of patients using a prospectively designed database. Univariate and multivariate logistic regression analyses were performed to identify the potential risk factors for the fever after PCNL.Results: Of the included 546 PCNL patients, there were 82 fever patients and 464 no-fever patients following PCNL. Escherichia coli and Proteus mirabilis are the two most common infectious bacteria.

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Section: Discussionmentioning

confidence: 99%

Risk factors for the fever after percutaneous nephrolithotomy: a retrospective analysis

et al. 2020

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Risk factors for re-infection in patients after drainage of the upper urinary tract due to obstructive pyelonephritis

et al. 2022

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Introduction. Reinfection after drainage of obstructive pyelonephritis exacerbates the postoperative course of the disease and delays the possible surgical intervention aimed at eliminating the cause of obstruction.Objectives. To determine the percentage of re-infection in patients drained with double-J stent or nephrostomy catheter for obstructive pyelonephritis. To assess the relationship between the timing of drainage removal and development of re-infection. To establish risk factors for the development of re-infection.Materials and methods. Medical records from 1022 patients who were treated from January 2019 to December 2021 and underwent drainage for obstructive pyelonephritis. The data in patients after nephrostomy and stenting were evaluated separately. A retrospective analysis of the time and frequency of the development of re-infection, as well as the effect of diabetes mellitus on pyelonephritis relapse, was carried out.Results. Re-infection during drainage developed in 16 (4.8%) patients with a nephrostomy and 45 (6.5%) patients with a stent. Among those who had re-infection in the nephrostomy-group, 4 (25.0%) patients noted it within two weeks from the moment of drainage, and 11 (69.0%) at three-four weeks. In the stent-group, the number of patients who had a complication during the first two weeks was 15 (33.0%), and it was 22 (49.0%) during the next two weeks, The proportion of patients with diabetes mellitus was higher among those who developed pyelonephritis again.Conclusion. The percentage of patients hospitalized with clinical re-infection after drainage of the upper urinary tract was 6.0%. There was an increase in the number of hospitalizations with recurrent pyelonephritis in cases where the drainage period lasted more than two weeks (p < 0.05).

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Acute obstructive pyelonephritis: prognosis of inflammatory response regression

Mamaev,

Saypulaev,

Dolomanov

et al. 2024

Vestn. Urol.

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Introduction. Predicting the timing of inflammation control in acute obstructive pyelonephritis based on routine laboratory values is of great importance. This is essential for planning the next stage of management to eliminate the cause of obstruction.Objective. To evaluate the dynamics and prognostic value of systemic inflammatory response markers in the management of acute obstructive pyelonephritis (AOP).Materials & methods. We performed a prospective study of the dynamics of inflammatory markers in patients with AOP. The study included 113 patients with AOP. Nephrostomy tube was installed in 43 and ureteral stent in 70. Following parameters were assessed: leukocytosis, CRP, creatinine on the days 1-3-7 after drainage, duration of fever. The risk factors for long-term regression of leukocytosis were also investigated.Results. On post-op day 3, the average leukocytosis was 10.5 (± 2.46) *109, and 68.1% of patients are returned to normal leukocyte level, and on post-op day 7 — 7.9 (± 3.12) *109 and 75.2%, respectively. On post-op day 3, the average CRP level was 14.2 (± 63.95) mg/l, and 32.7% of patients had decrease to target values, on post-op day 7 — 13.1 (± 49.7) mg/l and 56.6%, respectively. On post-op day 6, fever resolved in 98% of patients. Diabetes mellitus was the only statistically significant factor that can influence the long persistence of leukocytosis (p < 0.05).Conclusion. Leukocytosis showed higher specificity as a marker of inflammatory regression than CRP for AOP treatment. On post-op day 7, 75% of patients demonstrated laboratory and clinical signs for the inflammatory process relief. The presence of diabetes mellitus significantly prolongs the regression of the inflammatory response.

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Early Stone Manipulation in Urinary Tract Infection Associated with Obstructing Nephrolithiasis

Cited by 3 publications

References 18 publications

Risk factors for the fever after percutaneous nephrolithotomy: a retrospective analysis

Risk factors for the fever after percutaneous nephrolithotomy: a retrospective analysis

Risk factors for re-infection in patients after drainage of the upper urinary tract due to obstructive pyelonephritis

Acute obstructive pyelonephritis: prognosis of inflammatory response regression

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