Early structural deterioration with the mitroflow pericardial Xenograft in the mitral position

Bernal, José Manuel López; Rabasa, José; Echevarría, José Ramón Llanes; Revuelta, José M.

doi:10.1016/0003-4975(92)91167-8

Cited by 7 publications

(2 citation statements)

References 3 publications

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“…These devices are also associated with higher thrombogenicity. 2 As time went on, it was observed that cardiac bioprostheses that required simple or no maintenance presented early tears or structural degeneration, with or without calcium deposits, and that their durability was limited; [3][4][5] thus, there was a return to the use of mechanical prostheses, at least in Western countries.…”

Section: Introductionmentioning

confidence: 97%

“…14,15 Other authors suggest that the tears are also caused by the abrasion of the leaflet where it rubs against the Dacron fabric covering the ring, potentiating the harmful effect of the suture. 4,[15][16][17] The search for a biomaterial that is more resistant than those employed to date led the researchers to perform mechanical assays in ostrich pericardium. The initial results with respect to its resistance to rupture and its mechanical behavior were encouraging.…”

Section: Introductionmentioning

confidence: 99%

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Resistance to tearing of calf and ostrich pericardium: Influence of the type of suture material and the direction of the suture line

Páez¹,

Carrera²,

Jorge³

et al. 2004

J Biomed Mater Res

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The tearing of the valve leaflet of a cardiac bioprosthesis can cause early failure of this device, which is employed to replace a diseased native valve. This report involves the study of the behavior of 312 tissue samples (152 of calf pericardium and 160 of ostrich pericardium) treated with glutaraldehyde and subsequently subjected to tear testing. The samples were cut in the two principal directions: longitudinally, or root to apex, and transversely. They included a series of control samples that were left unsutured, and the remaining samples were repaired with the use of two different suture techniques: a running suture in the direction of the load and a telescoping suture perpendicular to the load. Four commercially available suture materials were employed: Pronova, nylon, Gore-Tex, or silk. The unsutured control samples of both types of pericardium exhibited a similar anisotropic behavior in the tear test. The mean resistance to tearing of the calf pericardium was 24.29 kN m in samples cut longitudinally and 34.78 kN m in those cut transversely (p =.03); the values were 28.08 kN m and 37.12 kN m (p =.002), respectively, in ostrich pericardium. The series repaired with the telescoping suture always exhibited greater resistance to tearing, with values that ranged between 44.34 and 64.27 kN for the samples of calf pericardium and from 41.65 to 47.65 kN for those obtained from ostrich. These assays confirm the anisotropic behavior of calf and ostrich pericardium treated with glutaraldehyde when subjected to tear testing, as well as the loss of this behavior in ostrich pericardium after suturing. Suturing techniques, such as the telescoping model, that provide a greater resistance to tearing should be studied for use in the design of the valve leaflets of cardiac bioprostheses made of biological materials.

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